arXiv AI

Decision and System One models in rheumatology: accuracy and calibration on specialty-training examination questions and diagnostic case vignettes

The study evaluated the accuracy and calibration of several Decision and System One models on rheumatology specialty‑training exam questions and diagnostic vignettes. On the RheumaMIR exam dataset, Jev achieved 93.0% accuracy in Spanish and 91.9% in English, while GPT‑6 Sol reached 99.4%. On the RheumBench diagnostic vignettes, GPT‑6 Sol again led with 76.9% accuracy, with Jev and other System One models scoring significantly lower (50.0%–59.6%).

arXiv AI
Oct 2

Jev in Medicine: A Benchmark Evaluation

The study evaluates Jev 1.13, a non‑generative model that selects from predefined answer options, on four medical benchmarks: MetaMedQA, PubMedQA, DiagnosisArena‑MCQ, and the NEJM Case Challenges. Jev’s top‑1 accuracy matches GPT‑6 Sol with medium reasoning on PubMedQA but falls behind on MetaMedQA, DiagnosisArena‑MCQ, and NEJM cases. While Jev shows strong calibration on MetaMedQA and is fast and inexpensive, its performance on examination and complex diagnostic tasks is substantially lower, indicating the need for task‑specific validation before clinical deployment.

By Alfredo Madrid-Garc\'ia, Beatriz Merino-Barbancho
arXiv Machine Learning
Oct 23

The Value of System 1 Models in Medicine

The study evaluates four zero‑shot System 1 models on 86 public clinical tasks across 14 domains and 20 languages, measuring performance via AUROC. The best models achieved high AUROC scores—0.94 for medical knowledge, 0.93 for text understanding, 0.83 for clinical judgement from text, 0.89 for image perception, 0.84 for 2D image findings, and 0.69 for volumetric findings—yet performed worse on imaging tasks and varied significantly with language. System 1 models were fast (0.34–0.44 s) and energy‑efficient (24–81 J) but lagged behind clinicians on triage and were outperformed by generative models in some metrics.

By Xiufeng Yang, Konstantinos Vrettos, Zeineb Ben Chaaben, Fabian Drexel, Jannik L\"ubberstedt, Johannes Moll, Anirudh Narayanan, Frederike Stumpf, Cosmin I. Bercea, Jiawen Wang, Evangelia E. Vassalou, Krischan Braitsch, Sebastian Ziegelmayer, Markus Graf, Marcus R. Makowski, Lisa Adams, Nassir Navab, Michail E. Klontzas, Keno Bressem
arXiv AI
Aug 13

A corpus-specific clinical RAG system matches or outperforms newer frontier LLMs on HealthBench

arXiv:2608. 12138v1 Announce Type: cross Abstract: General-purpose large language models (LLMs) have recently been reported to match or exceed specialized clinical AI tools on medical benchmarks, but such comparisons draw on a narrow set of systems and on benchmarks developed largely in high-income settings.

By Praveen Reddy, Charuta Mandke, Suvrankar Datta, Sarah Khan, Siddharth Reddy Anthireddy, Shitij Arora, Vishal Singh
arXiv Machine Learning
Oct 16

Calibrated Evidence Inference With a Small, Permissively Licensed Open Model

The paper presents a calibrated evidence inference model fine‑tuned from Qwen3‑4B‑Base using low‑rank adapters and a classification head to classify trial outcomes as significant increase, significant decrease, or no significant difference. Trained on 1,431 open‑access PubMed Central articles, the released model (Apache 2.0) achieves an expected calibration error of 0.017, a log loss lower than Gemma 4 31B‑it in zero‑shot settings, and a macro‑F1 of 0.925 on the test split. Accepting its top‑80 % most confident predictions yields only a 2.6 % error rate, and ablation studies show that article context influences answers while the title alone still provides useful signal.

By Johann Emmanuel Li
arXiv AI
Sep 15

Option-Aware Retrieval and Task-Specific VLM Adaptation for Medical VQA

The paper presents a system for the MedReason 2026 challenge that tackles both multiple‑choice and open‑ended medical visual question answering using offline, containerized inference. Key findings include that comparing answer semantics rather than labels boosts retrieval‑only accuracy from 20.0 % to 57.5 % on a 200‑case holdout, and that varying the number of in‑prompt retrieved examples has minimal impact on final accuracy (93.5 %–94.0 %). The final system achieves 94.0 % MCQ accuracy on the development set and 93.20 % on the official pre‑evaluation, far surpassing the off‑the‑shelf baseline. "whyItMatters":"The results demonstrate that semantic‑aware retrieval and careful adapter tuning can dramatically improve medical VQA performance, offering a practical approach for high‑accuracy, offline inference in clinical settings."

By Tristan Kirscher (ICube, Institut Strauss), Niklas C. Koser (CAU), Soren Pirk (CAU)
arXiv Machine Learning
Oct 7

Calibrated Answers About Randomized Trials From a 4-Billion-Parameter Open Model: A Registered Test and a License-Clean Release

Fiorillo v0.5 is an open 4‑billion‑parameter model that reads a randomized trial article (cut to 6,144 tokens) and predicts whether an intervention significantly increased, decreased, or had no significant effect on an outcome. Fine‑tuned on 1,431 license‑clean training articles, it achieved an expected calibration error of 0.0168, log loss 0.8603 lower than the prior, and macro‑F1 of 0.9248 on a public test split of 1,218 prompts. The model’s release, licensed under Apache 2.0, met all four pre‑registered criteria on the Open Science Framework and was validated against the evaluated predictions.

By Johann Emmanuel Li