arXiv AI

A Multi-Analyst LLM Pipeline for Auditable Rule Discovery Across 68 Public Physiological Corpora

arXiv:2607. 06802v1 Announce Type: cross Abstract: Open physiological corpora are heterogeneous: they use different sensors, labels, sampling rates, recording settings, and clinical endpoints.

arXiv Machine Learning
Sep 22

SafeTune: A Unified Faithful Library for Auditing and Repairing Safety Drift in Fine-Tuned LLMs

SafeTune is a source‑available library that consolidates four safety‑intervention paradigms—post‑hoc weight recovery, safety‑constrained fine‑tuning, gradient‑based unlearning, and inference‑time steering—into a single, configuration‑driven workflow. It offers shared interpretability, evaluation, and deployment tools, and its modular registry allows easy addition of new methods, benchmarks, judges, models, and fine‑tuning domains. The authors demonstrate SafeTune with controlled comparisons and case studies in finance and medical deployments, showing how it characterizes safety drift, evaluates interventions on refusal‑behavior and capability metrics, and supports calibrated or layered mitigation.

By Pratinav Seth, Saisab Sadhu, Anshul Kaushal, Vinay Kumar Sankarapu
arXiv AI
Aug 19

Institution-Specific LLM Prompting Recovers PHI That De-identification Systems and Their Gold Standards Both Miss

The study evaluates whether large language models (LLMs) with in‑context learning can better identify institution‑specific protected health information (PHI) in electronic health records than existing de‑identification systems. Using 100 pediatric oncology notes from Texas Children’s Hospital, eight LLMs were compared to two purpose‑built systems and pattern‑based baselines under three progressively specific prompts. The best LLM achieved an F1 score of 0.918, recovering 79% of previously missed PHI categories and reaching a recall of 0.981 after iterative prompt refinement, demonstrating that calibrated single‑pass prompting can close the institutional PHI gap while balancing precision and recall.

By Daniel Palacios, Matthew Brady Neeley, Angel Adetomike Otto, Shalini Dhamodharan, John P. Woodhouse, Chi-fan Lin, Mark Zobeck, Zhandong Liu, Hyun-Hwan Jeong
arXiv AI
2d ago

Can LLMs Reliably Annotate Bioassay Metadata to Improve Data Readiness?

arXiv:2610.01616v1 Announce Type: cross Abstract: The emergence of foundation models for molecular property prediction requires a high degree of AI data readiness, including reliable metadata annotat...

By Laura van Weesep, Riccardo Tedoldi, Jens Sj\"olund, Hossein Azizpour, Susanne Winiwarter, Ola Engkvist, Jon Paul Janet, Samuel Genheden, Juan Viguera Diez
arXiv Computation and Language
Aug 28

Benchmarking Clinical Decision Pathway Adherence in Large Language Models

The paper introduces MEGA-CDP, a benchmark designed to evaluate medical large language models (LLMs) on their ability to generate clinical decision pathways (CDPs) that adhere to clinical practice guidelines. MEGA-CDP is built from 2,274 English and Chinese guidelines, producing 42,353 clinical cases with explicit reference CDPs, and supports both single-turn and multi-turn interactions. Experiments on 16 LLMs reveal that reliable guideline adherence remains difficult, underscoring the need for CDP-focused evaluation and the potential of MEGA-CDP to advance medical LLM performance.

By Nuo Chen, Xinyang Jiang, Zilong Wang, Zhifei Zhang, Xiaoye Qu, Jiajun Deng, Yulan Guo, Cairong Zhao
arXiv AI
Aug 28

Evaluating human and LLM screening workflows in a conceptually complex scoping review: Recall--workload trade-offs and run-to-run consistency

The study compared human and large language model (LLM) workflows for title‑and‑abstract screening in a complex scoping review. Human reviewers and two GPT‑5.4 file‑batch runs retained 42.2‑45.0% of records with 82.3‑82.9% recall, while Gemini 3.1 achieved the highest recall (83.9%) but retained 56.7% of records. Identical GPT‑5.4 runs showed 91.7% agreement yet differed on 94 records, including 29 verified eligible ones.

By Nikol Figalov\'a, Lynn Huestegge, Anne B\"ockler-Raettig