The paper introduces Finsler Flow Matching (FFM), a method for learning continuous stochastic dynamics from discrete Markov transition graphs in single‑cell snapshot data. FFM constructs a Finsler geometry using first and second local moments, learns directed geodesics via neural networks, and employs these to build geometry‑aware stochastic paths that can be simulated without explicit score or flow matching. Benchmark tests show that FFM better recovers intermediate cellular states, especially when dynamics are directional or anisotropic.
arXiv:2608. 03967v1 Announce Type: cross Abstract: Generative Flow Networks (GFlowNets) have emerged as a flexible framework for amortised inference over discrete and mixed discrete-continuous objects, requiring only an unnormalised target density specified through a reward.
arXiv:2605.12805v2 Announce Type: replace-cross Abstract: MeanFlow enables one-step generation in continuous spaces by learning an average velocity over a time interval rather than the instantaneous...
arXiv:2608.21070v1 Announce Type: cross Abstract: Inferring continuous system evolution from sparse temporal snapshots is a key challenge in generative modeling and single-cell omics. While Optimal T...
arXiv:2510.01159v3 Announce Type: replace Abstract: Learning the dynamics of a process given sampled observations at several time points is an important but difficult task in many scientific applicat...
ReSFlow is a generative model that learns geodesic trajectories on statistical manifolds to enable one‑step categorical generation. By rectifying continuous‑time flows to follow intrinsic Riemannian geometry, it reduces transport cost and eliminates the need for multi‑step numerical integration. Experiments across image, text, and biological datasets show that ReSFlow achieves superior one‑step generation quality compared to prior methods.
arXiv:2606. 11286v1 Announce Type: cross Abstract: High-content imaging assays quantify cellular responses to chemical and genetic perturbations, yet continuous trajectories of individual cells are unobservable because cells are chemically fixed at acquisition.
arXiv:2609. 06947v1 Announce Type: new Abstract: Flow matching, together with classifier-free guidance (CFG), is widely used in generative modeling, yet much of the theoretical understanding remains distribution-wise.
The paper proposes a continuous‑time generative framework that models time‑dependent data as evolution on a learned data manifold. By using pretrained score‑based models as geometric priors, it learns a vector field that drives data along score‑induced interpolation paths, enabling generation at arbitrary timestamps and temporal super‑resolution. The method includes a regression‑based training objective, a stability‑promoting term interpreted as denoising score matching, and a probabilistic extension for future trajectory distributions, demonstrated on natural video, PDE‑based fields, and molecular dynamics.
arXiv:2609.38364v1 Announce Type: cross Abstract: Discrete diffusion models and flow matching have emerged as powerful frameworks for generative modeling over discrete state spaces, yet efficient few...
arXiv:2610.01193v1 Announce Type: cross Abstract: Counterfactual generation seeks to sample outcomes under a hypothetical intervention or decision using observational data collected under the factual...
arXiv:2606. 16073v1 Announce Type: new Abstract: Sampling from complex, unnormalized probability densities is a fundamental challenge in Bayesian inference and probabilistic modeling.
The paper introduces scEGFlow, an energy‑guided flow matching framework that predicts how single cells respond to perturbations by modeling continuous transitions from control to perturbed states. It uses conditional flow matching and condition‑specific energy gradients to dynamically adjust predictions without retraining, achieving superior performance on imaging and transcriptomic benchmarks, even for unseen perturbations or limited data. The method preserves cellular manifold geometry, heterogeneity, and accurately recapitulates gene‑expression regulatory patterns.