arXiv:2607. 22114v1 Announce Type: new Abstract: Autoregressive foundation models for electronic health records (EHRs) typically inherit pretraining methods from language modeling, where patient trajectories are concatenated into a single token stream and windows are sampled from that stream.
arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.
arXiv:2609.36144v1 Announce Type: new Abstract: Electronic health records provide irregular observations of latent patient states that evolve continuously over time. Recent autoregressive models cond...
arXiv:2602. 00541v2 Announce Type: replace Abstract: Clinical events captured in Electronic Health Records (EHR) are irregularly sampled and may consist of a mixture of discrete events and numerical measurements, such as laboratory values or treatment dosages.
arXiv:2607. 22264v1 Announce Type: new Abstract: Autoregressive foundation models trained on tokenized electronic health records (EHRs) can support zero-shot clinical prediction, yet most operate on structured event codes alone, and do not incorporate multiple modalities in a principled way.
MedFlow is a class‑aware multi‑scale flow matching framework designed to synthesize medical time‑series data. It uses a vector‑quantized multi‑scale tokenizer to capture both coarse and fine temporal patterns, and introduces Token Marginal Guidance to steer generation toward minority‑class characteristics. Experiments on four public datasets show MedFlow outperforms diffusion baselines, improving AUPRC by 5.8%, reducing Context‑FID by 88.6%, and achieving 3.8× higher sampling throughput.
arXiv:2609.37587v1 Announce Type: cross Abstract: Longitudinal electronic health record (EHR) modeling requires integrating new visits with an expanding patient history. Yet the continual accumulatio...
The paper introduces Scaling Electronic Health Record Foundation Models for Population Health Management, a large‑scale model trained on billions of medical events from over 5 million patients in Taiwan and the United States. By aligning ICD codes across different health systems, the model achieves strong scaling and generalization across 11 chronic disease prediction tasks, outperforming tree‑based, general, and biomedical language models with high sensitivity at 99% specificity. It also demonstrates superior few‑shot performance on the EHRShot benchmark and shows that cross‑system alignment provides a stronger pretraining signal than single‑site duplication in data‑limited scenarios.
The paper proposes a reinforcement learning (RL) fine‑tuning framework for electronic health record (EHR) foundation models, treating them as generative policies over patient trajectories. By framing clinical prediction tasks such as hospital readmission as event‑conditioned, time‑windowed reasoning problems and designing time‑aware, rollout‑sensitive rewards, the authors show that RL fine‑tuning consistently outperforms pre‑trained backbones and strong baselines. The approach enables smaller models to surpass larger pre‑trained models in data‑limited settings, induces positive transfer across tasks, and produces trajectories with stronger structural and semantic alignment to ground truth, improving downstream utility.
arXiv:2607. 12645v1 Announce Type: new Abstract: Generative modeling of longitudinal Electronic Health Records is increasingly important for privacy-preserving research, yet standard autoregressive models tend to underrepresent the co-occurrence structure of tail events (i.
arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.
Generative modeling of longitudinal Electronic Health Records is increasingly important for privacy-preserving research, yet standard autoregressive models tend to underrepresent the co-occurrence structure of tail events (i. e.
arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).