The paper identifies a new problem in clinical natural language processing called the clinical lost‑in‑the‑middle (CLitM) effect, where large language models perform poorly on information located near the center of long electronic health record (EHR) documents. Using the MedAlign dataset, the authors quantify a 21.9‑percentage‑point accuracy gap across 2,196 instruction‑response pairs and six models, showing that most critical facts lie in the CLitM trough. They propose Query‑Conditioned Clinical Suppression (QCCS), a lightweight context‑selection gate that outperforms traditional retrieval methods (BM25, dense retrieval, cross‑encoder reranking) on a held‑out set of 83 instructions, achieving up to 25.3% accuracy for middle‑position queries. whyItMatters":"The study demonstrates that standard retrieval strategies fail to reliably surface central clinical information, and that a query‑aligned selection mechanism can substantially improve model performance on critical EHR data."
arXiv:2609.14825v1 Announce Type: cross Abstract: Large language models (LLMs) are often deemed unsafe for clinical question answering because of their tendency to hallucinate. Retrieval augmentation...
arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).
arXiv:2606. 16890v1 Announce Type: cross Abstract: Aggregate accuracy benchmarks conceal a systematic structure in how large language models fail at electronic health record (EHR) question answering: questions requiring more inferential steps produce disproportionately more errors.
arXiv:2607. 04223v1 Announce Type: cross Abstract: Retrieval-augmented generation (RAG) reduces but does not eliminate hallucination, and existing detectors return a single answer-level score that does not indicate which sentence is unsupported, or why.
The paper introduces a retrieval‑augmented multi‑agent framework that automatically generates instance‑specific evaluation rubrics for medical language models. By retrieving authoritative medical evidence, decomposing it into atomic facts, and combining these with user interaction constraints, the system produces fine‑grained criteria that outperform GPT‑4o on HealthBench and LLMEval‑Med. The generated rubrics also guide response refinement, improving medical LLM output quality by 9.2%.
arXiv:2604. 04593v2 Announce Type: replace-cross Abstract: Retrieval-augmented generation (RAG) grounds large language models in external medical knowledge, yet standard retrievers frequently surface hard negatives that are semantically close to the query but describe clinically distinct conditions.
arXiv:2606. 15449v1 Announce Type: cross Abstract: Electronic prior authorization workflows require FHIR Questionnaire items to carry LOINC codes, yet most items in the HL7 Da Vinci CDS-Library lack these bindings.
arXiv:2608. 12138v1 Announce Type: cross Abstract: General-purpose large language models (LLMs) have recently been reported to match or exceed specialized clinical AI tools on medical benchmarks, but such comparisons draw on a narrow set of systems and on benchmarks developed largely in high-income settings.
arXiv:2606. 23992v1 Announce Type: cross Abstract: Clinical value sets define the standardized terminology codes used in quality measurement, phenotyping, cohort construction, and clinical decision support.
The paper presents a system for the MedReason 2026 challenge that tackles both multiple‑choice and open‑ended medical visual question answering using offline, containerized inference. Key findings include that comparing answer semantics rather than labels boosts retrieval‑only accuracy from 20.0 % to 57.5 % on a 200‑case holdout, and that varying the number of in‑prompt retrieved examples has minimal impact on final accuracy (93.5 %–94.0 %). The final system achieves 94.0 % MCQ accuracy on the development set and 93.20 % on the official pre‑evaluation, far surpassing the off‑the‑shelf baseline. "whyItMatters":"The results demonstrate that semantic‑aware retrieval and careful adapter tuning can dramatically improve medical VQA performance, offering a practical approach for high‑accuracy, offline inference in clinical settings."
arXiv:2606. 05970v1 Announce Type: cross Abstract: Large language models are increasingly used for structured extraction from clinical free-text notes, but the sensitivity of their output to upstream configuration choices is less understood than their accuracy on fixed benchmarks.
arXiv:2608. 14551v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for title-abstract screening in systematic reviews, but their decisions lack calibrated uncertainty.