PaReGTA is a large‑language‑model based framework that transforms longitudinal electronic health record events into visit‑level templated text with explicit temporal cues, learns visit embeddings through lightweight contrastive fine‑tuning, and aggregates them into fixed‑dimensional patient representations using hybrid temporal pooling. These representations can be fed into conventional machine‑learning models. In a cohort of 39,088 migraine patients from the All of Us Research Program, PaReGTA combined with LightGBM achieved the highest AUC, accuracy, and F1 scores on a held‑out test set compared to sparse, BERT‑based, and recurrent approaches.
arXiv:2608.21673v1 Announce Type: cross Abstract: Longitudinal electronic health records (EHRs) document patients' sequences of clinical visits over time, preserving the temporal evolution of disease...
arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.
arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.
Masked language modelling (MLM) remains the dominant pretraining objective for transformer encoders on longitudinal electronic health records (EHRs), but reconstructing individual events can overemphasise noisy observations and fails to encourage learning higher‑level patient states. Joint‑Embedding Predictive Architectures (JEPAs), which predict representations in latent space, were tested on MIMIC‑IV data and, while training stably, consistently underperformed standard MLM. The study found that larger target sizes increase prediction error, yet reducing target size does not improve downstream performance, indicating that stable latent prediction alone is insufficient for competitive EHR representation learning and underscoring the difficulty of defining clinically meaningful latent targets for EHR.
arXiv:2609.37587v1 Announce Type: cross Abstract: Longitudinal electronic health record (EHR) modeling requires integrating new visits with an expanding patient history. Yet the continual accumulatio...
arXiv:2608. 06430v1 Announce Type: new Abstract: Learning from Electronic Health Records (EHRs) has gained significant attention due to its potential to improve clinical prediction.
arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.
arXiv:2602. 00541v2 Announce Type: replace Abstract: Clinical events captured in Electronic Health Records (EHR) are irregularly sampled and may consist of a mixture of discrete events and numerical measurements, such as laboratory values or treatment dosages.
arXiv:2610.04946v2 Announce Type: replace Abstract: Cross-system transfer of longitudinal Electronic Health Record (EHR) representations is challenging because clinical coding, patient populations, a...
arXiv:2610.07388v1 Announce Type: cross Abstract: Joint Models simultaneously model longitudinal and survival outcomes, leveraging patterns in patients' longitudinal trajectory to improve the predict...
EHRAdapt is an adapter that maps electronic health record tuples directly into a frozen language model’s embedding space, using learned embeddings for modality, time gaps, and dedicated vectors for event codes. It represents each event vector as a sum of a frozen, ontology‑trained semantic prior and a low‑rank evidence residual, enabling robust learning even for rare clinical events. Experiments on four million patient records with three large language model backbones show that the full adapter outperforms all ablations in next‑event prediction and improves rare‑disease discrimination in classification tasks.
arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).