arXiv:2607. 15080v1 Announce Type: new Abstract: This article explores the application of covariate balance diagnostics for detecting the presence of hidden confounding/model miss-specification in studies applying offline reinforcement learning (RL) to deriving optimal treatment recommendations.
arXiv:2510. 01460v4 Announce Type: replace-cross Abstract: Offline-to-online reinforcement learning (RL) has emerged as a practical paradigm that leverages offline datasets for pretraining and online interactions for fine-tuning.
arXiv:2606. 20206v1 Announce Type: cross Abstract: In offline Reinforcement Learning, immediate rewards in logged batch data are often unobserved due to sparse or irregular record-keeping, or censored beyond certain reward values.
arXiv:2608. 03606v1 Announce Type: new Abstract: Clinical development is sequential decision-making under uncertainty, where a sponsor must plan a portfolio of experiments from heterogeneous evidence.
arXiv:2607. 11720v1 Announce Type: cross Abstract: Background: Offline reinforcement learning (RL) enables effective policies to be trained from large, previously collected datasets and subsequently improved through limited online interaction.
Background: Offline reinforcement learning (RL) enables effective policies to be trained from large, previously collected datasets and subsequently improved through limited online interaction. This offline-to-online RL (O2O-RL) paradigm is particularly promising in nonstationary domains where interaction is costly or potentially hazardous.
arXiv:2505. 22442v3 Announce Type: replace-cross Abstract: Offline RL (ORL) promises safe and sample-efficient deployment but existing methods rely on undocumented online interactions for hyperparameter tuning and lack reliable fully offline estimates of initial online performance.
arXiv:2606. 01028v1 Announce Type: new Abstract: Medical treatment recommendation poses several challenges to reinforcement learning (RL): patient physiology evolves in continuous time, measurements and interventions are performed at irregular intervals, and treatment effects vary substantially across individuals.
arXiv:2605. 12410v2 Announce Type: replace-cross Abstract: We propose and analyze a model-based bootstrap for transition kernels in finite controlled Markov chains (CMCs) with possibly nonstationary or history-dependent control policies, a setting that arises naturally in offline reinforcement learning (RL) when the behavior policy generating the data is unknown.
arXiv:2506. 00818v2 Announce Type: replace-cross Abstract: Offline reinforcement learning for longitudinal studies often faces two linked challenges: rewards may be binary or bounded, and reward observations may be available only for a subset of trajectories or time points even when the corresponding state-action-next-state histories are available.
arXiv:2608. 16482v1 Announce Type: new Abstract: The dosing of intravenous fluids and vasopressors in sepsis is a sequential decision made under uncertainty and guided largely by clinical judgment, which makes it a natural target for reinforcement learning from historical care.
arXiv:2606. 03332v1 Announce Type: new Abstract: Probabilistic models are typically trained using task-agnostic objectives like log-loss, which can lead to significant errors in downstream estimation.
arXiv:2606. 04305v1 Announce Type: new Abstract: We study online learning with an additional offline dataset in the stochastic linear bandit setting.