arXiv AI

Decision language models as affordable and rapid alternatives to LLM judges of clinical generative AI

The article reports on a study comparing Jev, a decision language model that provides structured judgments, with large language model (LLM) judges for evaluating clinical AI outputs. Across multiple use cases—including pediatric answer quality, binary HealthBench criteria, MedHELM open‑ended tasks, and HealthBench Professional—Jev matched or exceeded the performance of several frontier and open‑weight LLM judges. Moreover, Jev was significantly cheaper and faster, costing 73–294 times less and taking 7–57 times less time than frontier judges, suggesting it could enable efficient, scalable clinical AI evaluation.

arXiv AI
Jun 15

Can LLMs Accurately Score Medical Diagnoses and Clinical Reasoning?

arXiv:2604. 14892v3 Announce Type: replace-cross Abstract: Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators.

By Amy Rouillard, Sitwala Mundia, Linda Camara, Ziyaad Dangor, Michael Cameron Gramanie, Ismail Kalla, Shabir A. Madhi, Kajal Morar, Marlvin T. Ncube, Haroon Saloojee, Bruce A. Bassett
arXiv AI
Oct 16

AI Consilium: a Benchmark of LLM Clinical Multidisciplinary Second Opinions

The paper introduces AI Consilium, a benchmark for evaluating large language models (LLMs) on providing clinically grounded, coherent, actionable, and safe second opinions in multidisciplinary settings. Using 300 NEJM–MedQA cases, the study compares eight single-model pipelines that generate role-specific opinions and interactive-consilium reports under free-form and structured conditions. Results show that structured final reports generally score higher, especially in management, and that GPT‑5.6‑Sol outperforms other models across all evaluated components, demonstrating the benchmark’s ability to differentiate model capabilities and the impact of response structure.

By Alexey A. Bokov, Ivan I. Panin, Nikolay B. Nechaev, Mikhail Yu. Valkov, Valeria Yu. Chernina, Natalia Gombolevskaya, Ayyaz Hussain, Vladimir M. Agafonov, Victor A. Gombolevskiy, Aleksandr V. Nesterov, Iaroslav R. Bespalov, Ivan V. Oseledets, Dmitry V. Dylov
arXiv AI
Aug 13

A corpus-specific clinical RAG system matches or outperforms newer frontier LLMs on HealthBench

arXiv:2608. 12138v1 Announce Type: cross Abstract: General-purpose large language models (LLMs) have recently been reported to match or exceed specialized clinical AI tools on medical benchmarks, but such comparisons draw on a narrow set of systems and on benchmarks developed largely in high-income settings.

By Praveen Reddy, Charuta Mandke, Suvrankar Datta, Sarah Khan, Siddharth Reddy Anthireddy, Shitij Arora, Vishal Singh
arXiv AI
Jul 28

OpenAIs HealthBench in Action: Evaluating an LLM-Based Medical Assistant on Realistic Clinical Queries

arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.

By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv Computation and Language
Sep 21

JudgeSense: A Benchmark for Prompt Sensitivity in LLM-as-a-Judge Systems

JudgeSense is a benchmark comprising 880 items from human‑labelled corpora, each presented under two differently worded instructions that ask the same question. The study evaluates 25 judges from six providers across four tasks, measuring how rewording affects agreement with the judge’s own verdicts. Results show that rewording reduces agreement on all tasks, with significant effects on two, and that stability varies across tasks and is not predicted by parameter count.

By Rohith Reddy Bellibatlu, Edward Raff, Wenbin Zhang
arXiv AI
Oct 2

Scaling Clinical Judgment to Evaluate Medical AI

The paper introduces PrecepTron, a 32‑billion‑parameter language model fine‑tuned with low‑rank adaptation to evaluate clinical reasoning in large language models (LLMs) at a physician level. It also releases GRAND‑ROUNDS, a benchmark of 9,217 scored responses from 160 clinicians across seven studies. Using PrecepTron, the authors replicate key findings from major medical AI studies and explore new questions about LLM diagnostic accuracy, demonstrating that fine‑tuned models can provide consistent, scalable physician‑level scoring.

By Thomas A. Buckley, Zahir Kanjee, Peter G. Brodeur, Byron Crowe, Anthony M. Pettinato, Aashna P. Shah, Adrian D. Haimovich, Liam G. McCoy, Daniel Restrepo, Jason A. Freed, Ethan Goh, Jonathan H. Chen, Laura Zwaan, Katherine E. Goodman, Daniel J. Morgan, Raja-Elie E. Abdulnour, Adam Rodman, Arjun K. Manrai
arXiv AI
Oct 21

A general-purpose System One decision model for clinical records

The paper introduces Clinical System One (CS1), a 4‑billion‑parameter decision model that rapidly produces typed judgments from clinical records. Trained on 12.4 million Q&A pairs from 3.6 million patients, CS1 can answer multiple questions in a single forward pass, providing probability estimates for uncertain cases. In evaluations on 963,408 held‑out patients and 21 external datasets, CS1 outperformed larger open models and, when paired with a language‑model agent, efficiently identified trial‑eligible patients with far fewer tokens.

By Andrew Zhang, Trinh T. L. Vuong, Sophia J. Wagner, Dongmin Bang, Tong Ding, Yuchang Su, Mary Cipperman, Christina S. Chen, Judith Lefkes, Ramin Kahidi, Ming Y. Lu, Caiwei Tian, Tianhao Luo, Jingnan Ma, Rowland Pettit, Long Phi Le, Faisal Mahmood
arXiv AI
Jul 15

First, do NOHARM: a medical safety benchmark and randomized study of physician and AI teaming on clinical consultations

arXiv:2512. 01241v4 Announce Type: replace-cross Abstract: Large language models (LLMs) and medical AI tools are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.

By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh