ThuRunel is an AI advisory agent designed for high‑stakes domains that exhibit a two‑phase interaction structure: an initial empathetic elicitation phase followed by a specialist judgment phase. It uses a finite‑state belief management framework, a chain‑of‑thought teacher synthesis protocol, and learned generation adapters to dynamically decide what to ask, when to stop, what to resolve autonomously, and what to forward to a specialist. In evaluations against eleven baselines, ThuRunel consistently improves elicitation completeness and the quality of specialist briefs, and it is publicly deployed as a bilingual web application that cites its knowledge base in every answer.
arXiv:2608. 13476v1 Announce Type: new Abstract: We present Multi-Agent Reasoning and Coordination (MARC), an open-source framework that replaces monolithic LLM prompting with deterministic multi-agent orchestration for clinical reasoning.
The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.
arXiv:2608.22615v1 Announce Type: new Abstract: Large Language Model (LLM)-based counseling agents can generate fluent and supportive responses, but they often lack the structured, goal-directed prog...
arXiv:2609.22249v1 Announce Type: new Abstract: This paper treats prompt engineering as a discipline for turning informal human intent into structured AI work specifications. It develops the practice...
The paper reviews how Large Language Models (LLMs) are being adapted for medical reasoning, moving beyond single-step answers to systems that can systematically, transparently, and verifiably reason. It introduces a taxonomy of enhancement techniques, split into training-time methods such as supervised fine‑tuning and reinforcement learning, and test-time methods like prompt engineering and multi‑agent systems. The review examines their application across text, image, and code modalities in key clinical areas—diagnosis, education, and treatment planning—and tracks the shift in evaluation benchmarks from simple accuracy to more nuanced assessments of reasoning quality and visual interpretability.
arXiv:2603. 02070v3 Announce Type: replace Abstract: When automating plan generation for a real-world sequential decision problem, the goal is often not to replace the human planner, but to facilitate an iterative reasoning and elicitation process, where the human's role is to guide the AI planner according to their preferences and expertise.
arXiv:2606. 08938v1 Announce Type: cross Abstract: Clinical diagnosis requires flexible use of multiple reasoning paradigms under incomplete patient information.
arXiv:2509. 23071v2 Announce Type: replace-cross Abstract: Retrieval-augmented generation (RAG) agent development is hindered by the lack of executable ground-truth agent-environment interaction trajectories.
The paper introduces SIC-Agents, a self‑improving framework designed to enhance simulation for pediatric serious illness communication (SIC) training. It presents two new benchmark suites—PitfallBench and DialogueBench—that assess simulators at both turn‑level and full‑dialogue levels, specifically addressing the unique challenges of multi‑party interactions and parental distress. Experiments demonstrate that SIC‑Agents surpasses static expert prompting, and the authors release the benchmarks for broader research use.
The paper introduces CoRPS-Dial, a dual-agent framework that synthesizes pre‑consultation medical dialogues by combining a persona‑driven patient agent with a process‑guided doctor agent. It incorporates post‑hoc quality control to ensure role consistency, workflow completeness, and textual consistency. Experiments on coronary heart disease data show that CoRPS‑Dial produces dialogues that better match real conversations in information coverage, clinical compliance, and naturalness, and that the synthetic data improves downstream medical dialogue tasks.
ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.
Agentick is a unified benchmark for sequential decision‑making agents that evaluates RL, LLM, VLM, hybrid, and human agents on 37 procedurally generated tasks across six capability categories, four difficulty levels, and five observation modalities via a single Gymnasium‑compatible interface. It includes a Coding API, oracle reference policies, pre‑built SFT datasets, a composable agent harness, and a live leaderboard. An evaluation of 27 configurations and over 90,000 episodes shows no single approach dominates, with GPT‑5 mini leading overall, PPO excelling in planning and multi‑agent tasks, and the reasoning harness boosting LLM performance by 3‑10×, while ASCII observations outperform natural language.