Uncovering repurposed medicines to fight liver fibrosis
Stanford geneticist uses Co-Scientist to help find new treatments for chronic liver disease and liver fibrosis.
Filippo Menolascina uses Co-Scientist to identify new liver disease treatments and explain why existing drugs only help certain patients.
Stanford geneticist uses Co-Scientist to help find new treatments for chronic liver disease and liver fibrosis.
arXiv:2607. 02944v1 Announce Type: cross Abstract: We propose PRECEDE, a precedent-guided co-scientist for side-effect-aware drug redesign that revises a parent compound to mitigate a specified side effect while preserving therapeutic function.
arXiv:2502. 18864v2 Announce Type: replace Abstract: Scientific discovery is driven by scientists generating novel hypotheses for complex problems that undergo rigorous experimental validation.
Clare Bryant uses Co-Scientist to identify genetic triggers in emerging infectious diseases.
arXiv:2607. 11084v1 Announce Type: new Abstract: Agentic research systems are emerging as a new paradigm for coordinating scientific workflows beyond isolated model inference, code generation, or statistical analysis.
OpenAI introduces GPT-Rosalind, a frontier reasoning model built to accelerate drug discovery, genomics analysis, protein reasoning, and scientific research workflows.
arXiv:2607. 23975v1 Announce Type: new Abstract: Large language model research agents can connect literature retrieval, analysis code, and manuscript preparation, but coherent output does not establish scientific validity.
Calico Life Sciences uses Co-Scientist to connect scattered findings and generate new leads in aging research.
Large language model research agents can connect literature retrieval, analysis code, and manuscript preparation, but coherent output does not establish scientific validity. We developed Plato-Bio, a biology-routed extension of the open Plato/Denario architecture that couples explicit workflow states with provenance records, citation checks, claim-to-evidence links, scoped file writes, and publication gates.
arXiv:2608. 14969v1 Announce Type: new Abstract: We present a physiology-informed digital twin of the human liver designed for longitudinal simulation of liver function and early-stage disease progression.
Biologists use Co-Scientist to find novel factors that successfully rejuvenate human cells.
arXiv:2606. 31085v1 Announce Type: new Abstract: Drug-drug interaction (DDI) prediction is essential for medication safety, yet it requires reasoning over heterogeneous biomedical evidence whose relevance changes across interaction mechanisms.