arXiv Machine Learning

Score-based diffusion models for severely ill-posed problems in diffuse optical tomography

Score-based diffusion models, a recent framework for posterior sampling in Bayesian inverse problems, are applied to diffuse optical tomography (DOT), a highly ill‑posed boundary value problem for recovering tissue absorption and scattering. The authors introduce a mixed score that combines a learned component with a model‑based component, providing a theoretical justification for its local approximation to the true score in the small diffusion‑time regime. Four difference‑imaging approaches are compared—classical model‑based, approximate diffusion, exact posterior sampling (UCoS), and a regularized UCoS—showing that UCoS yields more accurate reconstructions, especially under limited‑view geometry and real experimental data.

arXiv AI
Sep 4

A Posterior-Dynamics Framework for Imaging Inverse Problems with Pretrained Diffusion Priors

The paper introduces a Posterior‑Dynamics Framework that leverages pretrained diffusion models as multiscale priors for linear imaging inverse problems such as deblurring, super‑resolution, and inpainting. By constructing a surrogate likelihood centered on the clean image and incorporating diffusion uncertainty, the authors derive continuous posterior dynamics and a tunable Langevin component for adaptive exploration. They prove theoretical guarantees (endpoint consistency, finite‑horizon tracking, weak accuracy) and present the PD‑IMEX sampler, which achieves high‑quality reconstructions with only 100 score evaluations and controllable fidelity‑diversity trade‑offs.

By Zhaoqiang Liu, Tongyao Pang, Ruibing Wang, Yang Zheng
arXiv Machine Learning
5d ago

Learning-Based Reconstruction of Optical Properties in Bilayered Media from Single-distance Time-Resolved Reflectance Measurements

The paper presents a machine‑learning framework for reconstructing absorption and scattering coefficients in bilayered biological media from single‑distance, time‑resolved reflectance data. By training on a synthetic dataset generated with exact Monte Carlo simulations, the method outperforms traditional diffusion‑equation‑based inverse solvers in both speed and accuracy. It also estimates the dimensionality of the parameter space without prior knowledge of the number of layers, and suggests that future work could further improve accuracy using multi‑distance data.

By Caterina Amendola, Giulia Maffeis, Lorenzo Buffoni, Lorenzo Chicchi, Francesco Coghi, Duccio Fanelli, Raffaele Marino, Fabrizio Martelli, Riccardo Paoli, Lorenzo Pattelli, Lorenzo Spinelli
arXiv Computer Vision
Sep 2

Diffusion Based Unpaired Data Learning for Inverse Problems

The paper introduces LUD-DIF, a diffusion-based method that solves inverse problems using unpaired data. By deriving the evidence lower bound of the joint distribution and decoupling it into two independent diffusion processes under a weak‑coupling assumption, the authors provide a variational inference framework, a loss function, and an error‑bound analysis. Experiments show that LUD‑DIF performs well across multiple image inverse problems, demonstrating its effectiveness and generalization in unpaired settings.

By Chenglong Bao, Yiming Dang, Chenguang Duan, Yuling Jiao, Defeng Sun