arXiv:2608. 14355v1 Announce Type: new Abstract: Spatial transcriptomics (ST) enables the simultaneous profiling of gene expression and tissue morphology, creating an opportunity to learn multimodal representations capturing shared morpho-transcriptomic structure.
By Julian Ostermaier, Swann Ruyter, Reuben Dorent, Daniel Racoceanu
arXiv:2606. 18703v1 Announce Type: new Abstract: Pretrained biological language models expose per-token probability distributions through masked-token prediction, providing the likelihood interface central to sequence design, variant scoring, and mechanistic interpretation.
By Yanjun Shao, Yundi Chen, Yashvi Patel, Aurelien Pelissier, Mar\'ia Rodr\'iguez Mart\'inez
arXiv:2605. 00025v3 Announce Type: replace-cross Abstract: Speech neuroprosthesis systems decode intended speech from neural activity in the absence of audible output, offering a path to restoring communication for individuals with speech-impairing conditions.
By Yuanhao Chen, Peter Chin
arXiv:2608. 00985v1 Announce Type: new Abstract: The rapid growth of single-cell transcriptomic data has enabled the development of foundation models pretrained primarily by reconstructing masked expression values.
By Jiaqi Xiong, Yuntao hu, Yu Zheng, Yifei Shi, Xinyue Guo, Jiaxin Qi
Neural State Prediction (NSP) is a latent‑predictive framework designed to curb shortcut learning in EEG foundation models. By using a target encoder updated with an exponential moving average, identity residualization, and topology‑separated context, NSP constrains both the prediction target and the available context. Trained on 2.2 million EEG segments, NSP outperforms baselines on 14 datasets in the EEG‑FM‑Bench, achieving 63.94 % macro balanced accuracy.
By Kieren Yu, Ziyang Liu, Chang Huang, Jintai Chen, Kaishun Wu
arXiv:2608.24597v1 Announce Type: cross
Abstract: Electroencephalography (EEG) is a widely used window into human brain function, but most EEG models remain tied to a one-dataset-one-model supervised...
By Yulong Dou, Han Wu, Guo Chen, Fangmao Ju, Zhiming Cui, Dinggang Shen
Brain4FMs is a unified benchmark for evaluating brain foundation models (BFMs) on both scalp EEG and intracranial EEG (iEEG). It incorporates 17 representative models and 21 public datasets spanning clinical diagnosis, sleep staging, communication, and affective computing, and offers dataset-aware preprocessing, cross‑subject evaluation, and standardized downstream workflows. The benchmark highlights that no single BFM consistently outperforms others across all tasks, modalities, and adaptation protocols, prompting further exploratory analyses of model‑specific spatial, spectral, and discrete representations.
By Fanqi Shen, Enhong Yang, Jiahe Li, Junru Hong, Xiaoran Pan, Zhizhang Yuan, Meng Li, Yang Yang
arXiv:2608. 02070v1 Announce Type: cross Abstract: Brain-computer interfaces (BCIs) have been widely used in motor rehabilitation, disease diagnosis, and other neural engineering scenarios.
By Zhu Chen, Dingkun Liu, Yuheng Chen, Dongrui Wu
arXiv:2608. 02070v2 Announce Type: replace-cross Abstract: Brain-computer interfaces (BCIs) have been widely used in motor rehabilitation, disease diagnosis, and other neural engineering scenarios.
By Zhu Chen, Dingkun Liu, Yuheng Chen, Dongrui Wu
arXiv:2607. 01656v1 Announce Type: new Abstract: The interaction between brain structure and genetic influences is key to understanding neuropsychiatric disorders.
By Jueqi Wang, Zachary Jacokes, John Darrell Van Horn, Kevin A. Pelphrey, Michael C. Schatz, Archana Venkataraman
The paper introduces Neuro‑JEPA, a sparse multimodal foundation model that learns unified representations of brain MRI across T1w, T2w, and FLAIR sequences using a latent predictive objective and a Mixture‑of‑Experts architecture. It was pretrained on over 1.5 million scans from 428,647 studies and systematically evaluates architectural, masking, objective, and sparsity choices for robust multimodal representation learning. Across 47 tasks from three health systems and 12 public datasets, Neuro‑JEPA consistently outperforms a simple CNN baseline, demonstrating its effectiveness for both clinical and research applications.
By Haoxu Huang, Long Chen, Jingyun Chen, Jinu Hyun, James Ryan Loftus, Kara Melmed, Daniel Orringer, Jennifer Frontera, Seena Dehkharghani, Arjun Masurkar, Narges Razavian
arXiv:2607. 21384v1 Announce Type: new Abstract: Electroencephalography (EEG) models used for epilepsy are often limited to specific datasets and tasks.
By Targol Bakhtiarvand, Jugal Kalita, Adham Atyabi