BenchBench‑Cloning is a new benchmark for evaluating large language models on end‑to‑end molecular cloning tasks. It contains 65 tasks drawn from real sequence records, laboratory notebooks, and published studies, split into 50 protocol‑development tasks and 15 construct‑design tasks. Performance is measured by simulation execution for protocols and deterministic or rubric‑based checks for design, with GPT‑6 Astra achieving the highest score of 30.6% among eight tested systems.
By Aditya Sivakumar, Peter Ciaccia, Hassaan Qadir, Ian Hsu, Ashu Singhal
PAPERBENCHX is a new benchmark that tests whether AI can reproduce scientific experiments across 12 disciplines, including electromagnetics, photonics, chemistry, materials science, biology, and robotics. It consists of 93 expert-constructed tasks, each providing a source paper, a public specification, and a domain-native scientific environment. The benchmark evaluates AI agents by having them reconstruct, execute, and diagnose key experiments, then replay submissions from scratch to score regenerated evidence against expert-validated criteria, revealing that current AI configurations fully reproduce only 14% of tasks.
By Ruoyu Wu, Zengji Tu, Aolong Sun, Tianyi Ma, Junren Li, Xinbo Xu, Li Fu, Ziyan Zhang, Pinrui Huang, Xiaochen Wang, Chengda Wu, Yutao Zhou, Jianjun Wu, Lin Chang, Baobao Chang, Liang Chen, Kuan Li
arXiv:2608.31076v1 Announce Type: cross
Abstract: Autonomous scientific research agents are increasingly applied to end-to-end scientific workflows, including literature review, data analysis, experi...
By Xuehai Wang, Haowei Qin, Tongxin Liu, Junkai Li, Buqiang Xu, Jintian Zhang, Yijun Chen, Zirui Xue, Shumin Deng
arXiv:2610.32441v1 Announce Type: new
Abstract: Large language model (LLM) agents are increasingly capable of supporting scientific workflows, but their capabilities across diverse research activitie...
By Tianyun Zhong, Wei Wang, Jialin Li, Jianhong Tu, Liyao Li, Chuqiao Kuang, Tianshi Zheng, Songchi Zhou, Weiqi Zhai, Qile Jin, Jiajia Li, Jiasheng Zheng, Boxi Cao, Yaojie Lu, Hongyu Lin, Shiwei Ye, Bing Zhao, Hu Wei, Lin Qu, Xianpei Han
Autonomous scientific research agents are increasingly applied to end-to-end scientific workflows, including literature review, data analysis, experimentation, and report generation. However, open-end...
arXiv:2609. 30971v1 Announce Type: new Abstract: Embodied agents offer a promising route to automating scientific experimentation, yet their progress is constrained by the lack of reliable and systematic evaluation environments.
By Maokai Qin, Chuan Qin, Qi Zhang, Dianyu Liu, Zirui Liu, Hongting Niu, Yuanchun Zhou, Hengshu Zhu
LiveMathematicianBench is a dynamic multiple‑choice benchmark for research‑level mathematical reasoning, built from recent arXiv papers published after model training cutoffs. It introduces a thirteen‑category logical taxonomy of theorem types and uses a proof‑sketch‑guided distractor pipeline to create plausible but invalid answer choices, enhancing sensitivity to genuine reasoning. Evaluation shows current large language models perform poorly, with the best model scoring 43.5% overall and only 17.6% under substitution‑resistant conditions, indicating the benchmark’s difficulty and realism.
By Linyang He, Qiyao Yu, Hanze Dong, Baohao Liao, Xinxing Xu, Micah Goldblum, Jiang Bian, Nima Mesgarani
arXiv:2607. 00436v1 Announce Type: new Abstract: Large language model agents are increasingly connected to scientific software, yet it remains unclear when tool access makes scientific computation more reliable rather than merely more complex.
By Ke Zhang, Sahchit Chundur, Mohammad Javad Qomi, Maziar Raissi
arXiv:2609.33357v2 Announce Type: replace
Abstract: Reliable automated research requires agents to vet data, verify analyses, and generate hypotheses grounded in trustworthy evidence, potentially red...
By Nan Huang, Mario Tapia-Pacheco, Kun Zhou, Yiming Huang, Kevin Jos\'e Barrientos D\'iaz, Tiffany Amariuta, Jingbo Shang
arXiv:2607. 06411v1 Announce Type: cross Abstract: Developers increasingly delegate real maintenance work to product-grade coding agents, and many state tasks in their native language, in the style of a customer request rather than a curated English issue.
By Evgeny Shilov (Independent Researcher)
arXiv:2606. 07591v1 Announce Type: cross Abstract: AI coding agents are increasingly used for scientific work, but their end-to-end autonomous research capability remains difficult to verify.
By Wanghan Xu, Shuo Li, Tianlin Ye, Qinglong Cao, Yixin Chen, Hengjian Gao, Yiheng Wang, Qi Li, Kun Li, Sheng Xu, Shengdu Chai, Fangchen Yu, Xiangyu Zhao, Zhangrui Zhao, Weijie Ma, Zijie Guo, Haoyu Zhou, Haoxiang Yin, Lixue Cheng, Chaofan Hu, Haoxuan Li, Lu Mi, Xuxuan Xie, Yifan Zhou, Ruizhe Chen, Zhiwang Zhou, Xingjian Guo, Yuhao Zhou, Xuming He, Shengyuan Xu, Xinyu Gu, Jiamin Wu, Mianxin Liu, Chunfeng Song, Fenghua Ling, Dongzhan Zhou, Shixiang Tang, Yuqiang Li, Mao Su, Peng Ye, Siqi Sun, Bin Wang, Xue Yang, Zhenfei Yin, Tianfan Fu, Guangtao Zhai, Wanli Ouyang, Bo Zhang, Lei Bai, Wenlong Zhang
arXiv:2608.21601v1 Announce Type: new
Abstract: Benchmarks for scientific artificial intelligence are mostly written to be scored: multiple-choice questions, curated agent tasks with reference soluti...
By Aubrey Brueckner, Darshil Patel, Yuhuan He, Timothy Kassis