arXiv:2608. 03731v1 Announce Type: new Abstract: Patient-facing medical LLMs and agents increasingly answer symptom questions before clinician contact, where the key safety question is what action the user should take next.
By Yining Hua, Hongbin Na, Cyrus Ayubcha
arXiv:2601. 17642v2 Announce Type: replace Abstract: Safety alignment in Large Language Models is critical for healthcare; however, reliance on binary refusal boundaries often results in over-refusal of benign queries or unsafe compliance with harmful ones.
By Zhihao Zhang, Liting Huang, Guanghao Wu, Preslav Nakov, Heng Ji, Usman Naseem
arXiv:2607. 28677v1 Announce Type: new Abstract: LLM now pass medical licensing examinations and, in curated cases, can rival physicians at diagnostic reasoning.
By Shayndhan Sivanathan, Shravan Nageswaran, Mehdi Zadem, Ryaan Sultan, Nicolas von Mallinckrodt, Max Solovyev, Alexey Matyushkin, Sumon Sadhu, Gabriele C DeLuca, Sanjeeva Jeyaretna, James Hillis, Manoj Ramachandran, Prakash Jayakumar
arXiv:2608. 10258v1 Announce Type: cross Abstract: Large language models (LLMs) increasingly provide conversational health information that may influence treatment decisions, yet existing benchmarks do not isolate whether medication-safety boundaries persist across follow-ups after explicit self-treatment intent.
By Waleed Jamil, Raphael Schmitt
AcuityBench is a new benchmark that tests whether language models can correctly identify the urgency of medical care needed from user presentations. It unifies five public datasets—user conversations, online forum posts, clinical vignettes, and patient portal messages—under a shared four-level acuity framework, providing 914 cases for evaluation. The benchmark supports both explicit four-way classification and free-form conversational responses, revealing that models vary widely in accuracy and that conversational formats reduce over-triage but increase under-triage, especially for high-acuity cases.
By Robin Linzmayer (Department of Computer Science, Columbia University, Department of Biomedical Informatics, Columbia University), Georgianna Lin (Department of Biomedical Informatics, Columbia University), Di Coneybeare (Department of Emergency Medicine, Columbia University Irving Medical Center), Jason Chu (Department of Emergency Medicine, Columbia University Irving Medical Center), Trudi Cloyd (Department of Emergency Medicine, Columbia University Irving Medical Center), Manish Garg (Department of Emergency Medicine, Columbia University Irving Medical Center), Miles Gordon (Department of Emergency Medicine, Columbia University Irving Medical Center), Elizabeth Hartofilis (Department of Emergency Medicine, Columbia University Irving Medical Center), Benjamin Hong (Department of Emergency Medicine, Columbia University Irving Medical Center), Ashraf Hussain (Department of Emergency Medicine, Columbia University Irving Medical Center), Eugene Y. Kim (Department of Emergency Medicine, Columbia University Irving Medical Center), Oluchi Iheagwara King (Department of Emergency Medicine, Columbia University Irving Medical Center), Ross McCormack (Department of Emergency Medicine, Columbia University Irving Medical Center), Erica Olsen (Department of Emergency Medicine, Columbia University Irving Medical Center), John K. Riggins Jr (Department of Emergency Medicine, Columbia University Irving Medical Center), Mustafa N. Rasheed (Department of Emergency Medicine, Columbia University Irving Medical Center), Dana L. Sacco (Department of Emergency Medicine, Columbia University Irving Medical Center), Vinay Saggar (Department of Emergency Medicine, Columbia University Irving Medical Center), Osman R. Sayan (Department of Emergency Medicine, Columbia University Irving Medical Center), Amit Shembekar (Department of Emergency Medicine, Columbia University Irving Medical Center), Janice Shin-Kim (Department of Emergency Medicine, Columbia University Irving Medical Center), Wendy W. Sun (Department of Emergency Medicine, Columbia University Irving Medical Center), Bernard P. Chang (Department of Emergency Medicine, Columbia University Irving Medical Center), David Kessler (Department of Emergency Medicine, Columbia University Irving Medical Center), No\'emie Elhadad (Department of Computer Science, Columbia University, Department of Biomedical Informatics, Columbia University)
arXiv:2508. 00923v3 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to answer health-related questions and support healthcare workflows, yet evidence for their safety still relies heavily on static benchmarks that can rapidly become obsolete or be optimized against.
By Jiazhen Pan (Cherise), Bailiang Jian (Cherise), Paul Hager (Cherise), Yundi Zhang (Cherise), Che Liu (Cherise), Friederike Jungmann (Cherise), Hongwei Bran Li (Cherise), Julian Canisius (Cherise), Chenyu You (Cherise), Junde Wu (Cherise), Jiayuan Zhu (Cherise), Fenglin Liu (Cherise), Yuyuan Liu (Cherise), Niklas Bubeck (Cherise), Moritz Knolle (Cherise), Chen (Cherise), Chen (Cherise), Christian Wachinger, Zhenyu Gong, Cheng Ouyang, Georgios Kaissis, Benedikt Wiestler, Daniel Rueckert