arXiv:2603. 14158v2 Announce Type: replace-cross Abstract: Large language models (LLMs) are entering clinical workflows, yet evaluations rarely assess how clinician reasoning shapes model behavior during clinical interactions.
By Ivan Lopez, Selin S. Everett, Bryan J. Bunning, April S. Liang, Dong Han Yao, Shivam C. Vedak, Kameron C. Black, Sophie Ostmeier, Stephen P. Ma, Emily Alsentzer, Jonathan H. Chen, Akshay S. Chaudhari, Eric Horvitz
arXiv:2512. 01241v4 Announce Type: replace-cross Abstract: Large language models (LLMs) and medical AI tools are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.
By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh
arXiv:2607. 13562v1 Announce Type: new Abstract: Knowing when to say "I don't know" is fundamental to human judgment, yet AI assistants offer a fluent answer to almost any question.
By Chiara Marcoccia, Walter Quattrociocchi, Valerio Capraro
Knowing when to say "I don't know" is fundamental to human judgment, yet AI assistants offer a fluent answer to almost any question. In five experiments (N = 3,132; four preregistered, one direct replication), participants answered difficult questions and could always decline to respond.
The paper investigates how human interventions at specific fault points—moments when an AI agent’s reasoning is most vulnerable—affect the diagnostic accuracy of multi‑agent medical systems. Using the MedQA dataset, the authors found that correct interventions can boost baseline accuracy by up to 40%, whereas incorrect or bias‑related interventions can reduce performance by up to 6% and increase diagnostic drift and uncertainty. The study also highlights behavioral parallels between cognitive biases observed in simulated agent conversations and real‑world clinical practice, such as premature closure and susceptibility to misleading cues.
By Benjamin C Liu, Dillon Mehta, Rishi Malhotra, Adam Zobian, Yong Ying Tan, Samir Chopra, Daniella Rand, Natalie Pang, Abhiram Gudimella, Kevin Zhu
arXiv:2205. 04599v2 Announce Type: replace-cross Abstract: Explainable Artificial Intelligence (XAI) is essential for trustworthy AI in healthcare, yet many existing methods rely on technical explanations that are difficult for clinicians and patients to interpret.
By Mohammad Eslami, Solale Tabarestani, Saber Kazeminasab, Ehsan Adeli, Glyn Elwyn, Tobias Elze, Mengyu Wang, Nazlee Zebardast, Lucia Sobrin, Nassir Navab, Daniel Shu Wei Ting, Malek Adjouadi