arXiv AI By Yuan-Hang Zhang, Chesson Sipling, Massimiliano Di Ventra

Scientific discovery as meta-optimization: a combinatorial optimization case study

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arXiv:2606. 26728v1 Announce Type: new Abstract: Scientific discovery is fundamentally an optimization problem, defined by a vast "state space" of theories and experiments, and an evaluation criterion based on quality, novelty, and validity.

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Scientific discovery as meta-optimization: a combinatorial optimization case study

Scientific discovery is fundamentally an optimization problem, defined by a vast "state space" of theories and experiments, and an evaluation criterion based on quality, novelty, and validity. Large language models (LLMs) have enabled automated exploration of this space, but we argue that simultaneous modification of the evaluation criteria is equally important.

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