Safe Domain Adaptation for Physics: Overcoming Nuisances, Label Shifts, and Simulation Priors

The paper introduces a new approach to domain adaptation in physics, addressing the fact that simulations often differ from experimental data not only in nuisances but also in the target quantity distribution. By studying a toy air‑shower benchmark with separate nuisance, simulation, and spectrum shifts, the authors show that standard adversarial adaptation can misalign spectra, leading to bias. They propose adaptive domain adaptation that reweights simulated events to focus on genuine physical mismatches and provide a label‑free rule for selecting the best model configuration.

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• fine-tuning
• benchmarks
• safety