ProtAgent: Post-Training Compact Protein Tool Agents with Interaction-Level Credit Assignment
Read the original on arXiv AI →The Flow has not summarised this story yet — read it at arXiv AI.
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arXiv:2609.36679v1 Announce Type: new Abstract: Machine learning engineering (MLE) agents have made substantial progress, but learning through ML experimentation remains costly in time and computatio...
arXiv:2606. 16517v1 Announce Type: new Abstract: Scientific reasoning models for biology combine language models with foundation models trained on multimodal biological data, including DNA, RNA, and proteins.
Scientific reasoning models for biology combine language models with foundation models trained on multimodal biological data, including DNA, RNA, and proteins. These models are built through post-training, yet how each stage shapes reasoning and generalization remains poorly understood.
The paper introduces OmicsBench, a new reasoning benchmark for multi‑omics sequences that includes 1,160 expert‑validated questions across DNA regulation, RNA processing, and protein function tasks, requiring traceable evidence chains. Evaluation of 17 large language models shows that scientific LLMs, while more accurate in classification, often lack valid evidence, suggesting shortcut learning. To address this, the authors propose tool‑augmented on‑policy distillation (TA‑OPD), a post‑training method that improves both evidence grounding and predictive performance across five Qwen3.5 models of varying sizes.
arXiv:2609.36641v1 Announce Type: cross Abstract: Process reward models (PRMs) have become a key component for LLMs, as their step-level feedback supports both post-training and test-time reasoning....
UniToolCall introduces a unified framework for tool-use in large language model agents, standardizing toolset construction, dataset generation, and evaluation. The framework aggregates over 22,000 tools and creates a hybrid training corpus of more than 390,000 instances by combining ten public datasets with synthetically generated, structurally controlled trajectories. It models diverse interaction patterns—single‑hop vs. multi‑hop, single‑turn vs. multi‑turn, serial vs. parallel execution—and adds an Anchor Linkage mechanism to enforce cross‑turn dependencies, while converting seven public benchmarks into a common Query–Action–Observation–Answer format for fine‑grained evaluation.