arXiv AI By Leo Y. Li-Han, Chris Varghese, Elizabeth B. Habermann, Mark J. Truty, William R. G. Perry, Cornelius A. Thiels, Hojjat Salehinejad

GraphBEAT: Graph-based Bucketized Event Aggregation Over Time for Early Risk Stratification of Gastrointestinal Cancers

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GraphBEAT is a temporal graph representation learning framework that bucketizes clinical events from longitudinal electronic health records into time‑ordered graphs, enabling early risk stratification for gastrointestinal cancers. It uses a time‑decay message‑passing mechanism and multi‑head attention pooling to generate patient‑level representations, and was trained on multi‑site diagnosis codes and laboratory tests to predict pancreatic, liver, and intestinal cancer at 12, 24, and 36‑month lead times. Across all experiments, GraphBEAT outperformed baseline graph neural networks and sequence models while requiring far fewer floating‑point operations and parameters.

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