arXiv AI
3d ago

Transcriptome-informed multi-modal AI for predicting neoadjuvant therapy response from breast cancer biopsies

arXiv:2610.03693v1 Announce Type: new Abstract: Scarcity of labeled data limits development of deep learning biomarkers in oncology. We develop a two-stage AI model predicting pathological complete r...

By Jungkyu Park, Dhruva Biswas, Joseph Cappadona, Cerise Tang, Ken G. Zeng, Bartosz Machura, Chuwen Liu, Paolo Tarantino, Coral Omene, Francisco J. Esteva, Rohit Bhargava, Marcin Braun, Kamila Pa\'zdzierz, Jakub Czerwi\'nski, Hanna Roma\'nska-Knight, Albert Grinshpun, Bareket Daniel, Michele Buchinger, Frederick Howard, Piotr Wysocki, Brie Chun, Freya Schnabel, Rich Caruana, Jan Witowski, Krzysztof J. Geras
arXiv Machine Learning
Jul 21

Tabular Foundation Models Can Do Survival Analysis

arXiv:2601. 22259v2 Announce Type: replace Abstract: While tabular foundation models have achieved remarkable success in classification and regression, adapting them to model time-to-event outcomes for survival analysis is non-trivial due to right-censoring, where data observations may end before the event of interest occurs.

By Da In Kim, Wei Siang Lai, Kelly W. Zhang
arXiv AI
Oct 1

CellMSA: Context Modeling for Single-Cell Representation Learning

CellMSA introduces a novel single‑cell representation learning framework that leverages a multiple‑sequence‑alignment‑inspired context model. For each target cell, it retrieves relevant cells across batches and related cell types, summarizing cross‑cell patterns into a context‑dependent gene‑pair representation that is fed into a pair‑aware encoder. Pretraining on a massive human single‑cell corpus (≈109 million cells) and subsequent benchmarks demonstrate consistent performance gains over existing methods.

By Suyuan Zhao, Minghao Liu, Yizhen Luo, Zaiqing Nie