arXiv AI By Shuai Wang, Yize Zhao, Qingyu Chen

CLEAR: Cross-Source Evidence Adjudication for Large Language Models in Medicine

Read the original on arXiv AI →

The paper introduces CLEAR, an agentic framework designed to improve the reliability of large language models (LLMs) in medical contexts by adjudicating evidence from multiple sources. CLEAR generates candidate answers from three distinct pathways—parametric knowledge, locally curated corpora, and dynamically retrieved evidence—and then uses an aggregation verifier to evaluate agreement and conflict among these sources. An adjudication module decides whether to preserve or revise conclusions, employing override-guard and challenge-audit mechanisms, and initiates targeted follow-up searches when conflicts remain unresolved.

Machine-generated by The Flow from the publisher's headline and feed description — not written or checked by a human. The full article lives at arXiv AI.

arXiv AI
Sep 2

Medical Causal Hypothesis Verification with Large Language Models

The paper "Medical Causal Hypothesis Verification with Large Language Models" reports a small-scale study evaluating eight LLMs on 17 medical causal hypotheses. The authors introduce an evaluation framework and annotate 1,067 evidence points across six criteria, using nine metrics to assess performance. Results show that while LLMs have strong recall, they frequently fail to provide valid scientific articles, evidence, or reject unsupported hypotheses, revealing a critical limitation for their use in healthcare.

By Safiyyah Ahmed, Abrar Ansari, Md Aminul Islam, Elena Zheleva
arXiv Computation and Language
Aug 24

MedRAGChecker: Claim-Level Verification for Biomedical Retrieval-Augmented Generation

MedRAGChecker is a claim-level verification framework designed for biomedical retrieval‑augmented generation (RAG). It decomposes generated answers into atomic claims and assesses each claim’s support by combining evidence‑grounded natural language inference with biomedical knowledge‑graph consistency signals. The aggregated claim decisions provide diagnostics that distinguish retrieval and generation failures, such as faithfulness, under‑evidence, contradiction, and safety‑critical errors, and the system is distilled into compact models for scalable evaluation.

By Yuelyu Ji, Min Gu Kwak, Hang Zhang, Xizhi Wu, Chenyu Li, Yanshan Wang
arXiv AI
Aug 26

Generating Biomedical Fact-Checking Reports with RL-Enhanced Agentic Search

The paper introduces BioCheck Agent, an LLM-based system that generates structured biomedical fact‑checking reports using agentic search and a reinforcement‑learning framework called EG‑GRPO. Unlike prior methods that output only supported or refuted labels, BioCheck Agent synthesizes conclusions with retrieved evidence from PubMed, employing advanced Boolean search operators. Experiments show that, compared to the base Qwen3.5‑4B model, BioCheck Agent improves label prediction accuracy on SciFact by 9.95 %, raises evidence quality by 3.7 %, and reduces hallucinations by 19.63 %.

By Jiongxiao Wang, Dingli Ma, Chaoqun Ni
arXiv Computation and Language
Aug 27

When Retrieval Helps and Distracts: Evaluating Evidence-Generating LLMs for Biomedical Claim Verification

The paper investigates evidence generation for biomedical claim verification, evaluating various large language models and retrieval strategies on the CARE-XAI benchmark. It finds that fine‑tuned LLMs excel at producing evidence, while biomedical classifiers still lead in verdict‑only prediction. PubMed retrieval helps on PubMed‑aligned datasets but can mislead on broader public‑health claims, prompting the authors to propose Bio‑GRACE, a diagnostic that normalizes gold references to assess retrieval utility.

By Pritam Deka, Prabhjot Singh
arXiv Computation and Language
Aug 27

Retrieval-Augmented Agentic Rubric Generation for Reliable Medical Response Evaluation

The paper introduces a retrieval‑augmented multi‑agent framework that automatically generates instance‑specific evaluation rubrics for medical language models. By retrieving authoritative medical evidence, decomposing it into atomic facts, and combining these with user interaction constraints, the system produces fine‑grained criteria that outperform GPT‑4o on HealthBench and LLMEval‑Med. The generated rubrics also guide response refinement, improving medical LLM output quality by 9.2%.

By Yinzhu Chen, Abdine Maiga, Hossein A. Rahmani, Emine Yilmaz