arXiv AI By Umberto Michelucci

An Introduction to Large Language Models for Scientists and Professionals

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The article introduces Large Language Models (LLMs) to scientists and professionals, covering core concepts such as tokenisation, embeddings, training, inference, context windows, prompting, and instruction hierarchies without delving into mathematics. It emphasizes the limitations of LLM outputs—hallucinations, uncertainty, reproducibility, bias—and stresses the importance of systematic verification, human oversight, and responsible handling of sensitive data. Practical exercises guide readers through running a local LLM with Ollama and Open WebUI, focusing on evidence retrieval, source verification, and distinguishing plausible language from scientifically supported conclusions.

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