The paper presents a newly curated, multi-center, multi-modal, and longitudinal lung cancer dataset comprising 1,365 patients with whole-slide images, CT scans, PET scans, structured clinical data, transcriptomics, and follow-up information. The dataset features substantial, non-uniform missingness across modalities, making it ideal for evaluating robust multi-modal fusion strategies. Benchmarks on 12‑month overall survival, disease‑specific survival, and longitudinal hazard prediction demonstrate that integrating complementary modalities consistently outperforms uni-modal approaches, even under severe missing data.
By Rita Cordeiro Mendes, Maria Rita Fonseca Verdelho, Carlos Santiago, Catarina Barata
arXiv:2608. 09240v1 Announce Type: cross Abstract: Multimodal federated learning (FL) supports collaborative modeling in privacy-sensitive health-sensing and medical settings, but realistic deployments often exhibit dual-axis modality missingness: clients have different modality sets, and individual samples may contain only subsets of the modalities available locally.
By Adiba Orzikulova, Jaehyun Kwak, Jaemin Shin, Yunqi Guo, Xiaomin Ouyang, Guoliang Xing, Steven Euijong Whang, Sung-Ju Lee
arXiv:2607. 09982v1 Announce Type: new Abstract: Electronic health record (EHR) data are inherently multimodal, and leveraging multiple modalities can improve predictive performance.
By Nikkie Hooman, Zhongjie Wu, Eric C. Larson, Mehak Gupta
arXiv:2607. 06633v1 Announce Type: cross Abstract: In this paper, we address the problem of multimodal federated learning with missing modality.
By Aavash Chhetri, Bibek Niroula, Eduard Vazquez, Yash Raj Shrestha, Prashnna Gyawali, Loris Bazzani, Binod Bhattarai
arXiv:2510. 07328v2 Announce Type: replace-cross Abstract: Medical decision systems increasingly rely on data from multiple sources to ensure reliable and unbiased diagnosis.
By Md Zubair, Hao Zheng, Grayson W. Armstrong, Lucy Q. Shen, Gabriela Wilson, Yu Tian, Xingquan Zhu
arXiv:2510.06113v2 Announce Type: replace
Abstract: Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which red...
By Shuo Jiang, Zhuwen Chen, Liaoman Xu, Yanming Zhu, Changmiao Wang, Jiong Zhang, Feiwei Qin, Yifei Chen, Zhu Zhu
arXiv:2603.08459v2 Announce Type: replace
Abstract: Safe predictions are a crucial requirement for integrating predictive models into clinical decision support systems. One approach to improving trus...
By L. Juli\'an Lechuga L\'opez, Tim G. J. Rudner, Farah E. Shamout
MODIS is a semi‑supervised framework for integrating multi‑omics data that are often unpaired, partially labeled, and scarce, such as in rare disease studies. It trains on a large reference database and a small target dataset simultaneously, using diagonal integration and class‑label alignment to handle class imbalance. The architecture combines variational auto‑encoders, a class classifier, and an adversarially trained modality classifier, with a regularized relativistic GAN loss for stable training, and demonstrates high accuracy on synthetic data and the TCGA cancer dataset.
By Daniel Lepe-Soltero, Thierry Arti\`eres, Ana\"is Baudot, Paul Villoutreix
arXiv:2607. 27289v1 Announce Type: new Abstract: The promise of multimodal fusion lies in combining complementary sources of evidence, yet more evidence does not always yield a better prediction.
By Yu Chang, Anzhe Cheng, Chenwei Wu, Zhuoran Wang, Jiahao Chen, Tamoghna Chattopadhyay, Sophia I. Thomopoulos, Paul M. Thompson, Liyue Shen, Paul Bogdan
arXiv:2609.14072v1 Announce Type: new
Abstract: Large Language Models (LLMs) have displayed impressive capabilities in handling tasks that require few demonstration examples, making them effective fe...
By H Mathavan, H Liu
arXiv:2606. 15743v1 Announce Type: new Abstract: This paper addresses the missing-modality challenge in multi-modal learning by introducing Unsupervised Learning for Missing Modalities in Multi-Modal Learning (UL4M4), a flexible framework that imputes missing feature embeddings in a task-independent manner before supervised prediction.
By Hassan Ismkhan, Hamid Bouchahcia
arXiv:2608. 02769v1 Announce Type: cross Abstract: Multimodal supervised learning seeks to leverage multiple heterogeneous data sources to improve predictive performance.
By Sagnik Nandy, Samriddha Lahiry, Pragya Sur, Subhabrata Sen