arXiv Machine Learning

A Fast Screening Approach for High-dimensional Outcomes and High-dimensional Predictors

arXiv:2606. 03018v1 Announce Type: cross Abstract: Modeling interactions among multimodal, high-dimensional data is intrinsically challenging due to ultra-high dimensionality and complex dependence structure with high level noise.

arXiv Machine Learning
Jun 5

Cross-scale spatially-aware generative modeling of transcriptomic programs underlying neurodegenerative brain organization

arXiv:2606. 05870v1 Announce Type: cross Abstract: Neurodegenerative disorders such as Alzheimer's disease exhibit highly organized patterns of regional brain vulnerability, yet the biological mechanisms underlying this spatial selectivity remain incompletely understood.

By Krishnakumar Vaithianathan (for the Alzheimer's Disease Neuroimaging Initiative)
arXiv Machine Learning
Jul 28

Dementia Etiology Diagnosis via Collaborative Meta Knowledge Enhancement

arXiv:2607. 22770v1 Announce Type: new Abstract: Although artificial intelligence (AI) has shown promising performance in several medical tasks, accurate dementia etiology diagnosis with AI remains challenging due to complex overlapping symptoms among diseases.

By Siyuan Du, Mengxi Chen, Xinyang Jiang, Zilong Wang, Jiangchao Yao, Dongsheng Li, Ya Zhang, Lili Qiu, Yanfeng Wang
arXiv Machine Learning
Jul 14

Imputation-free transformer learning enables robust Alzheimer's disease prediction and calibrated uncertainty quantification across heterogeneous clinical cohorts

arXiv:2607. 11656v1 Announce Type: cross Abstract: Accurate diagnostic classification and disease-severity prediction for Alzheimer's disease are hampered by the incompleteness and heterogeneity of real-world clinical data.

By Christelle Schneuwly Diaz, Narmina Baghirova, Duy-Thanh Vu, Duy-Cat Can, Gilles Allali, Philippe Ryvlin, Oliver Y. Ch\'en
arXiv AI
Jun 2

Brain-Atlas-Guided Generative Counterfactual Attention for Explainable Cognitive Decline Diagnosis Using Multimodal Connectomes

arXiv:2606. 01237v1 Announce Type: new Abstract: Mild cognitive impairment (MCI) and subjective cognitive decline (SCD) are closely associated with the early Alzheimer's disease continuum, where accurate and explainable diagnosis is important for early risk assessment and intervention.

By Xiongri Shen, Jiaqi Wang, Zhenxi Song, Yi Zhong, Leilei Zhao, Xin He, Baiying Lei, Zhiguo Zhang
arXiv AI
Jun 15

GMN4AD: Graph Matching Network for Alzheimer's Disease Diagnosis with Test-Time Domain Adaptation using Multi-centered Structure Magnetic Resonance Imaging

arXiv:2606. 13919v1 Announce Type: cross Abstract: Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that affects millions of older adults, with prevalence expected to rise significantly in the coming years.

By Chen Zhao, Huan Huang, Yixin Xie, Jiajing Huang, Weihua Zhou, Nandakumar Narayanan