The paper investigates whether clinical concepts are represented as distinct, causally influential centers within the latent space of large language models (LLMs). By evaluating eleven open-weight LLMs, the authors discover that each model contains dedicated clinical concept centers that are interpretable, activate only on relevant clinical narratives, and drive model behavior in both constrained and open-ended contexts. These centers can be leveraged for evaluation and performance improvement, as steering models along them enhances downstream clinical outcomes and aligns with clinician preferences.
arXiv:2606. 07237v1 Announce Type: cross Abstract: Large Language Models (LLMs) are increasingly used in healthcare for tasks such as clinical question answering, diagnosis support, and report summarization.
arXiv:2606. 14149v1 Announce Type: new Abstract: Large Language Models (LLMs) are increasingly deployed in healthcare settings, yet their tendency to hallucinate poses risks when clinical decisions are involved.
arXiv:2603. 14158v2 Announce Type: replace-cross Abstract: Large language models (LLMs) are entering clinical workflows, yet evaluations rarely assess how clinician reasoning shapes model behavior during clinical interactions.
The paper introduces PrecepTron, a 32‑billion‑parameter language model fine‑tuned with low‑rank adaptation to evaluate clinical reasoning in large language models (LLMs) at a physician level. It also releases GRAND‑ROUNDS, a benchmark of 9,217 scored responses from 160 clinicians across seven studies. Using PrecepTron, the authors replicate key findings from major medical AI studies and explore new questions about LLM diagnostic accuracy, demonstrating that fine‑tuned models can provide consistent, scalable physician‑level scoring.
arXiv:2601.12868v2 Announce Type: replace-cross Abstract: Large language models (LLMs) increasingly operate in high-stakes settings where demographic attributes such as race and ethnicity may be expl...
arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.
arXiv:2508. 00923v3 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to answer health-related questions and support healthcare workflows, yet evidence for their safety still relies heavily on static benchmarks that can rapidly become obsolete or be optimized against.
arXiv:2606. 32008v1 Announce Type: new Abstract: Mechanistic interpretability (MI) requires full access to model internals, yet the APIs for most widely deployed language models at best expose log-probabilities over output tokens.
arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.
arXiv:2605. 28969v2 Announce Type: replace-cross Abstract: If an AI agent makes decisions on a person's behalf, those decisions must align with its user.
arXiv:2601. 22588v2 Announce Type: replace-cross Abstract: Large language models (LLMs) are widely used as reference-free evaluators via prompting, but this "LLM-as-a-Judge" paradigm is costly, opaque, and sensitive to prompt design.
arXiv:2608.21766v1 Announce Type: cross Abstract: Both capability and safety benchmarks rest upon the assumption that the behavior of language models undergoing a test is informative about their beha...