arXiv AI

Resolving superposition in AI for interpretability and cross-modal alignment in patient-neuronal images

arXiv:2606. 31394v1 Announce Type: cross Abstract: Artificial intelligence is transforming our capability to solve biological challenges.

arXiv Machine Learning
Jun 5

Cross-scale spatially-aware generative modeling of transcriptomic programs underlying neurodegenerative brain organization

arXiv:2606. 05870v1 Announce Type: cross Abstract: Neurodegenerative disorders such as Alzheimer's disease exhibit highly organized patterns of regional brain vulnerability, yet the biological mechanisms underlying this spatial selectivity remain incompletely understood.

By Krishnakumar Vaithianathan (for the Alzheimer's Disease Neuroimaging Initiative)
arXiv Machine Learning
Jun 5

HEIST: A Graph Foundation Model for Spatial Transcriptomics and Proteomics Data

arXiv:2506. 11152v4 Announce Type: replace-cross Abstract: Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell level.

By Hiren Madhu, Jo\~ao Felipe Rocha, Tinglin Huang, Siddharth Viswanath, Smita Krishnaswamy, Rex Ying
arXiv Machine Learning
Jun 24

Similarity of Neural Network Representations in Superposition

arXiv:2604. 00208v2 Announce Type: replace Abstract: Comparing internal representations is a central goal in neuroscience and machine learning, but standard linear alignment metrics (Representational Similarity Analysis, Centered Kernel Alignment, and linear regression) are frequently applied to neural activity coordinates rather than on the underlying features.

By Sunny Liu, Habon Issa, Andr\'e Longon, Liv Gorton, Meenakshi Khosla, Alex Williams, David Klindt