arXiv AI

LegoSR: A Unified Framework for Self-improving Agent-Guided Scientific Discovery

Hugging Face Trending Papers
Jul 15

Automatic Ordinary Differential Equations Discovery For Biological Systems Using Large Language Model Powered Agentic System

Automatic scientific discovery has long been a goal of computational scholars - a machine that can discover nature's secrets on its own, moving computational systems beyond data-fitting tools toward the generation and refinement of mechanistic models of the universe. Recent advances in symbolic regression (SR) and large-language-model (LLM)-based agents suggest that such systems can recover equations from data, incorporate domain priors, and automate parts of the research workflow.

arXiv AI
Jul 16

Automatic Ordinary Differential Equations Discovery For Biological Systems Using Large Language Model Powered Agentic System

arXiv:2607. 13608v1 Announce Type: new Abstract: Automatic scientific discovery has long been a goal of computational scholars - a machine that can discover nature's secrets on its own, moving computational systems beyond data-fitting tools toward the generation and refinement of mechanistic models of the universe.

By David Krongauz, Arad Zulti, Eran Segal, Teddy Lazebnik
arXiv Machine Learning
Jun 4

Deliberate Evolution: Agentic Reasoning for Sample-Efficient Symbolic Regression with LLMs

arXiv:2606. 04360v1 Announce Type: cross Abstract: Symbolic regression (SR) discovers compact mathematical expressions from data, yet recent LLM-based evolutionary methods remain sample-inefficient because they rely mainly on scalar feedback such as MSE.

By Xinyu Pang, Zhanke Zhou, Xuan Li, Fangrui Lv, Shanshan Wei, Sen Cui, Bo Han, Changshui Zhang
arXiv Machine Learning
Oct 15

Beyond Equation Search: Conjecture-Guided Discovery with SCOPE and ClosureBench

The paper introduces SCOPE, a framework that enables multiple scientist agents to pursue conjecture-driven research trajectories by modeling equations, formulating questions, and conducting active experiments, then sharing evidence to refine their conjectures. It also presents ClosureBench, an interactive benchmark of 60 closure-discovery tasks across five scientific domains, designed to evaluate equation discovery beyond accuracy by measuring evidence faithfulness, mechanism insight, and experimental effectiveness. Experiments show that SCOPE outperforms diverse baselines on both ClosureBench and a real-world scientific discovery case, yielding more accurate, reliable, and effective scientific discoveries.

By Yuxiao Hu, Qian Li, Ding Wang, Siheng Chen, Linfeng Zhang, Jinyue Yan, Yuntian Chen
arXiv Machine Learning
Sep 21

MOSAIC-SR: Transformer-Guided Symbolic Regression for Scientific Equation Recovery

MOSAIC‑SR is a new symbolic regression method that combines a pretrained Transformer with search‑based refinement. The Transformer generates multiple initial sketches, which seed searches that jointly recover equation structure and constants using scale‑aware optimization and symbolic repair. On the SRSD‑Feynman dataset and six other benchmarks, MOSAIC‑SR achieves the highest symbolic solution rate and ranks among the top two in predictive accuracy, even when irrelevant dummy variables are present.

By Peiyi Zheng, Yanming Kang, Hans De Sterck, Giang Tran