arXiv:2606. 15419v1 Announce Type: cross Abstract: Objective: To enhance the accuracy, interpretability, and robustness of large language models (LLMs) in medical question answering (MedQA).
By Zaifu Zhan, Shuang Zhou, Rui Zhang
arXiv:2607. 06452v1 Announce Type: cross Abstract: Biomedical question answering requires not only accurate extraction of information from scientific literature but also reliable integration of evidence across multiple documents.
By Taeyun Roh, Eunha Lee, Wonjune Jang, Sohyun Chung, Junha Jung, Jaewoo Kang
The paper introduces an adaptive memory and reflection (AMR) multi‑agent system for medical question answering. Each agent has dedicated memory and uses reflection‑based feedback to retrieve relevant prior cases, improving reasoning. The system routes questions through solo, collaborative, or escalated workflows and includes consensus and ethical overseer modules, achieving strong performance on MedQA and MedMCQA datasets.
By Pradeep Murugesan, Luoxiao Yang, Xueli Chen, Xinqi Fan
The paper reviews how Large Language Models (LLMs) are being adapted for medical reasoning, moving beyond single-step answers to systems that can systematically, transparently, and verifiably reason. It introduces a taxonomy of enhancement techniques, split into training-time methods such as supervised fine‑tuning and reinforcement learning, and test-time methods like prompt engineering and multi‑agent systems. The review examines their application across text, image, and code modalities in key clinical areas—diagnosis, education, and treatment planning—and tracks the shift in evaluation benchmarks from simple accuracy to more nuanced assessments of reasoning quality and visual interpretability.
By Zizhan Ma, Wenxuan Wang, Meidan Ding, Shiyi Zheng, Shengyuan Liu, Jie Liu, Jiaming Ji, Linlin Shen, Yixuan Yuan, Wenting Chen
arXiv:2610.08327v1 Announce Type: new
Abstract: Large language models (LLMs) have shown promise in medical question answering and clinical reasoning, yet their improvement remains constrained by stat...
By Xilin Dang, Weilin Ruan, Xue Yang, Jinghao Wang, Xiaowei Hu, Jinpeng Li, Pheng-Ann Heng
arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.
By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv:2603. 03292v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields.
By Wenhao Wu, Zhentao Tang, Yafu Li, Shixiong Kai, Mingxuan Yuan, Zhenhong Sun, Chunlin Chen, Zhi Wang
arXiv:2503. 07459v3 Announce Type: replace-cross Abstract: Complex medical reasoning requires integrating heterogeneous clinical evidence across multiple inference steps.
By Yanjun Shao, Xiangru Tang, Jiwoong Sohn, Jiapeng Chen, Yuxuan Liao, Jiayi Zhang, Jinyu Xiang, Fang Wu, Yilun Zhao, Chenglin Wu, Wenqi Shi, Arman Cohan, Mark Gerstein
arXiv:2609.24480v1 Announce Type: cross
Abstract: Deploying Large Language Models (LLMs) in healthcare requires robust performance across two complementary dimensions - diagnostic reasoning: the conv...
By Kalash Shah, Kunal Singh, Snehan J, Shreyas Singh
The paper introduces LLM‑PeerReview, an unsupervised ensemble method that selects the best response from multiple LLM-generated candidates by scoring each answer with several LLMs, aggregating those scores via averaging or a graphical model, and choosing the highest-scoring response. The approach is peer‑review inspired, transparent, and interpretable, and it outperforms the Smoothie‑Global model by 6.9%–7.3% across factual recall QA, math reasoning, and instruction‑following tasks. The authors also provide a curated benchmark suite of 12 ensemble methods evaluated on four datasets and three task families to aid reproducibility.
By Zhijun Chen, Zeyu Ji, Qianren Mao, Hao Wu, Jinhuan Song, Junhang Cheng, Bangjie Qin, Zhuoran Li, Jingzheng Li, Kai Sun, Zizhe Wang, Yikun Ban, Zhu Sun, Xiangyang Ji, Hailong Sun, Xiao Huang
The paper introduces PrecepTron, a 32‑billion‑parameter language model fine‑tuned with low‑rank adaptation to evaluate clinical reasoning in large language models (LLMs) at a physician level. It also releases GRAND‑ROUNDS, a benchmark of 9,217 scored responses from 160 clinicians across seven studies. Using PrecepTron, the authors replicate key findings from major medical AI studies and explore new questions about LLM diagnostic accuracy, demonstrating that fine‑tuned models can provide consistent, scalable physician‑level scoring.
By Thomas A. Buckley, Zahir Kanjee, Peter G. Brodeur, Byron Crowe, Anthony M. Pettinato, Aashna P. Shah, Adrian D. Haimovich, Liam G. McCoy, Daniel Restrepo, Jason A. Freed, Ethan Goh, Jonathan H. Chen, Laura Zwaan, Katherine E. Goodman, Daniel J. Morgan, Raja-Elie E. Abdulnour, Adam Rodman, Arjun K. Manrai
arXiv:2507. 02983v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) hold significant promise for transforming digital health by enabling automated medical question answering.
By Mohammad Anas Azeez, Rafiq Ali, Ebad Shabbir, Zohaib Hasan Siddiqui, Gautam Siddharth Kashyap, Jiechao Gao, Usman Naseem