CliniCIRCA is a modular large‑language‑model framework that reconstructs longitudinal mental‑health patient journeys from raw electronic health record narratives. It temporally classifies clinical events in unstructured discharge summaries without explicit timestamps, producing 15,891 tagged events from 52 summaries and correcting 629 errors to create verified gold‑standard timelines. The framework then generates temporally grounded summaries, compressing each source by 1.52×, and scales to produce 1,000 silver‑standard timelines for training, showing that instruction tuning improves event extraction, temporal tagging, and summarization across models.
By Aiwei Ivy Zhang, Nimra Ishfaq, Mohit Chandra, Santiago Alvarez Lesmes, Adam Coscia, Khatiya Chelidze Moon, Xiaohan Ding, Munmun De Choudhury
The article surveys how large language models (LLMs) are being applied to mental health, outlining a three‑phase evolution: Phase I uses LLMs as passive information tools and pattern recognizers for assessment; Phase II employs them as empathetic conversationalists for stateless, in‑the‑moment interactions; Phase III aims to create longitudinal, personalized companions that act as stateful cognitive agents. It systematically reviews core technologies, agent architectures (Profile, Memory, Reasoning, Planning), and the datasets and benchmarks that support this progression, offering a coherent narrative and roadmap for future research. The survey also provides a curated resource list at https://github.com/Emo-gml/Awesome-Mental-Health-LLMs.
By He Hu, Yucheng Zhou, Qianning Wang, Yingjian Zou, Chiyuan Ma, Juzheng Si, Jianzhuang Liu, Zitong Yu, Laizhong Cui, Fei Ma, Qi Tian
The paper reviews how large language models are applied in mental health, covering areas such as social media analysis, clinical conversational agents, therapy support tools, prompt engineering, and multimodal learning. It synthesizes interdisciplinary studies that use social media posts, electronic medical records, and multimodal inputs to detect depression, assess suicide risk, provide personalized therapy, and generate psychoeducational content. The review also discusses advances in model interpretability, annotation strategies, multimodal fusion techniques, and highlights ethical, sociotechnical, and regulatory challenges while proposing frameworks for safe, equitable, and accountable deployment.
By Yisong Chen, Yifan Gao, Sijing Yu, Chuqing Zhao, Yang Lu
arXiv:2606. 27247v1 Announce Type: new Abstract: In NLP, mental health conditions are often modeled as isolated phenomena, without interpersonal context.
By Parmitha Vangapandu, Sai Ganesh Mokkapati, Sathwik Narkedimilli, MSVPJ Sathvik, Timothy Liu, Simon See, Johannes C. Eichstaedt
arXiv:2510.25384v2 Announce Type: replace
Abstract: Large Language Models (LLMs) are promising tools for synthetic data generation in mental health. However, privacy policies and restrictions forced...
By Doan Nam Long Vu, Rui Tan, Lena Moench, Svenja Jule Francke, Daniel Woiwod, Florian Thomas-Odenthal, Sanna Stroth, Tilo Kircher, Christiane Hermann, Udo Dannlowski, Hamidreza Jamalabadi, Simone Balloccu, Shaoxiong Ji
arXiv:2512. 06227v3 Announce Type: replace-cross Abstract: Real-world indicators play an important role in many Natural Language Processing (NLP) applications, such as life events for mental health analysis and risky behaviours for online safety, yet labelling such information is often costly and/or difficult due to its multi-label and dynamic nature.
By Junyu Mao, Anthony Hills, Talia Tseriotou, Maria Liakata, Aya Shamir, Dan Sayda, Dana Atzil-Slonim, Natalie Djohari, Pamela Ugwudike, Mahesan Niranjan, Stuart E. Middleton