arXiv Machine Learning By Tirtharaj Dash, Gunja Sachdeva

$p$-adic Bi-Filtrations for Topological Machine Learning on Genomic Sequences

Read the original on arXiv Machine Learning →

arXiv:2606. 06117v1 Announce Type: cross Abstract: We introduce pVR, a topological machine learning framework for alignment-free genomic sequence classification that combines $p$-adic numbers with topological data analysis.

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We introduce pVR, a topological machine learning framework for alignment-free genomic sequence classification that combines $p$-adic numbers with topological data analysis. Each DNA sequence is encoded along two complementary axes: a $p$-adic distance on $k$-mer prefixes, which captures hierarchical positional structure, and a compositional $L_1$ distance on $k$-mer frequencies, which captures local sequence content.

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