arXiv AI

Shaping Scientific Explanations to Expert Perspectives with Persona-Conditioned Reinforcement Learning

arXiv:2603. 21846v2 Announce Type: replace Abstract: Explainable AI is increasingly important to scientific discovery.

arXiv AI

Jul 1

DDIAgents: Mechanism-Conditioned Context Flow for Drug-Drug Interaction Prediction

arXiv:2606. 31085v1 Announce Type: new Abstract: Drug-drug interaction (DDI) prediction is essential for medication safety, yet it requires reasoning over heterogeneous biomedical evidence whose relevance changes across interaction mechanisms.

By Zhenqian Shen, Yu Liu, Xiaoyi Fu, Quanming Yao

llms agents benchmarks safety

arXiv AI

Jun 30

An AI agent for treatment reasoning over a biomedical tool universe

arXiv:2606. 28692v1 Announce Type: new Abstract: Treatment reasoning underpins every therapeutic decision, integrating disease context, comorbidities, medications, contraindications, and evolving biomedical knowledge to select an appropriate therapy.

By Shanghua Gao, Ayush Noori, Richard Zhu, Curtis Ginder, Zhenglun Kong, Xiaorui Su, Justin Kauffman, Benjamin S. Glicksberg, Joshua Lampert, Ankit Sakhuja, Ashwin Sawant, ATHENA-R1 Evaluation Consortium, David A. Clifton, Noa Dagan, Ran Balicer, Marinka Zitnik

llms agents reinforcement-learning fine-tuning benchmarks

arXiv AI

Jul 7

Reinforcement Learning for Evidence-Seeking Diagnostic Reasoning with Large Language Models

arXiv:2607. 02983v1 Announce Type: new Abstract: Recent reasoning-centric Large Language Models (LLMs) have made significant strides, yet they predominantly operate on a passive-inference pattern that assumes complete information.

By Shengyi Hua, Kangzhe Hu, Conghui He, Xiaofan Zhang, Shaoting Zhang

llms rag agents reinforcement-learning

arXiv AI

Jun 16

Retro-Expert: Collaborative Reasoning for Interpretable Retrosynthesis

arXiv:2508. 10967v3 Announce Type: replace-cross Abstract: Retrosynthesis prediction aims to infer the reactant molecules based on a given product molecule, which is a fundamental task in chemical synthesis.

By Xinyi Li, Sai Wang, Yutian Lin, Yu Wu

llms reinforcement-learning

arXiv AI

Jul 13

All Explanations are Wrong, But Many Are Useful: Exploring the Rashomon Explanation Set with Large Language Models

arXiv:2607. 09502v1 Announce Type: cross Abstract: Explaining machine-learning models is increasingly important for decision-making and consumer trust, yet it is widely believed to come at a cost: existing Explainable AI (XAI) methods suffer from a persistent accuracy-explainability trade-off.

By Pan Li

llms agents benchmarks

arXiv AI

Jun 2

Process Reward Agents for Steering Knowledge-Intensive Reasoning

arXiv:2604. 09482v2 Announce Type: replace Abstract: Reasoning in knowledge-intensive domains remains challenging as intermediate steps are often not locally verifiable: unlike math or code, evaluating step correctness may require synthesizing clues across large external knowledge sources.

By Jiwoong Sohn, Tomasz Sternal, Kenneth Styppa, Torsten Hoefler, Michael Moor

rag agents benchmarks

arXiv AI

Aug 5

HERO: Hierarchical Evidential Reasoning Optimization for Radiology Report Generation via Reason-then-Summarize

arXiv:2601. 03321v3 Announce Type: replace-cross Abstract: Multimodal Large Language Models (MLLMs) have substantially advanced Radiology Report Generation (RRG), yet aligning them through reinforcement learning (RL) remains challenging due to heterogeneous medical supervision.

By Kun Zhao, Guodong Liu, Hui Ji, Siyuan Dai, Pan Wang, Jifeng Song, Chenghua Lin, Liang Zhan, Haoteng Tang

llms reinforcement-learning multimodal benchmarks safety

arXiv AI

Jul 20

GraphDx: A Cost-Aware Knowledge-Enhanced Multi-Agent Framework for Sequential Diagnosis

arXiv:2607. 15280v1 Announce Type: new Abstract: Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering.

By Shaoting Tan, Ning Liu, Yuntao Du, Shuyue Wei, Wu Shuai, Qian Li, Yanyu Xu, Wei Zhang, Lizhen Cui, Haitao Yuan

llms agents efficiency

arXiv AI

Jul 17

CoEvoT: Co-Evolving Chain-of-Thought Prompting for Graph-LLM Reasoning

arXiv:2607. 14114v1 Announce Type: cross Abstract: Graph learning under distribution shift presents a persistent challenge, where models adapt to new graphs with limited or even no supervision.

By Haohua Niu, Xingtong Yu, Yang Liu, Junfeng Fang, Xuanting Xie, Jie Tan, Zhongjian Zhang, Hong Cheng, Yuan Fang

llms benchmarks

arXiv AI

Jul 2

Graph-Native Reinforcement Learning Enables Traceable Scientific Hypothesis Generation through Conceptual Recombination

arXiv:2607. 00924v1 Announce Type: new Abstract: Accelerating materials discovery requires AI systems that can generate scientifically valid hypotheses through multi-step, domain-grounded reasoning.

By Subhadeep Pal, Shashwat Sourav, Tirthankar Ghosal, Markus J. Buehler

llms rag reinforcement-learning fine-tuning safety

arXiv AI

Jun 30

Accelerating scientific discovery with Co-Scientist

arXiv:2502. 18864v2 Announce Type: replace Abstract: Scientific discovery is driven by scientists generating novel hypotheses for complex problems that undergo rigorous experimental validation.

By Juraj Gottweis, Wei-Hung Weng, Alexander Daryin, Tao Tu, Petar Sirkovic, Artiom Myaskovsky, Grzegorz Glowaty, Felix Weissenberger, Alessio Orlandi, Dan Popovici, Anil Palepu, Keran Rong, Ryutaro Tanno, Khaled Saab, Fan Zhang, Jacob Blum, Andrew Carroll, Kavita Kulkarni, Nenad Tomasev, Dina Zverinski, Ivor Rendulic, Elahe Vedadi, Florian Hasler, Luka Rimanic, Marina Boia, Ivan Budiselic, Ben Feinstein, Mathias Bellaiche, Tom Sheffer, Jan Freyberg, Jeremy Ratcliff, Ottavia Bertolli, Katherine Chou, Avinatan Hassidim, Burak Gokturk, Amin Vahdat, Yuan Guan, Vikram Dhillon, Eeshit Dhaval Vaishnav, Byron Lee, Tiago R D Costa, Jos\'e R Penad\'es, Gary Peltz, Yossi Matias, James Manyika, Demis Hassabis, Yunhan Xu, Pushmeet Kohli, Annalisa Pawlosky, Alan Karthikesalingam, Vivek Natarajan

llms agents

arXiv AI

Jul 13

Toward Auditable AI Scientists: A Hypothesis Evolution Protocol for LLM Agents

arXiv:2607. 09195v1 Announce Type: new Abstract: Large language model (LLM) agents are increasingly expected to play a central role in AI-driven scientific discovery.

By Izumi Takahara, Teruyasu Mizoguchi

llms agents

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