arXiv Machine Learning By Aron Asefaw, Konstantinos Tzevelekakis, Damian Falk, L\'eo Meynent, Damian Borth

WeightCLIP: Aligning Datasets and Models for Weight Space Learning

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arXiv:2607. 03551v1 Announce Type: new Abstract: Weight space learning aims to learn representations of neural network (NN) weights, enabling different downstream tasks.

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arXiv Machine Learning
Sep 4

SimpleDesign: A Joint Model for Protein Sequence and Structure Codesign

SimpleDesign is a single-stage, end-to-end model for joint protein sequence and structure design that eliminates the need for multi-stage training. It combines discrete cross-entropy for sequences with a regression objective for structures, using a Mixture-of-Transformer architecture to handle modality-specific processing while maintaining global self-attention. Trained on over 2 million sequence-structure pairs, SimpleDesign achieves strong performance on co-design and unconditional generation benchmarks.

By Jiarui Lu, Yuyang Wang, Yizhe Zhang, Jiatao Gu, Navdeep Jaitly, Joshua M. Susskind, Miguel \'Angel Bautista