arXiv:2607. 05613v1 Announce Type: new Abstract: Clinical care often relies on key laboratory indicators, yet real-world patient visits are sparse and tests are ordered irregularly, leading to pervasive missingness.
By Xinrui He, Mengting Ai, Junting Wang, Curtiss B. Cook, Jingrui He
RDDMPI introduces a residual denoising diffusion model for multivariate time series imputation. By decomposing the missing signal into a baseline reconstruction and a residual uncertainty component, the method conditions the diffusion process on both the completed signal and its latent representation, using a reliability-aware mechanism to balance baseline influence. Experiments on benchmark datasets show that this approach improves reconstruction accuracy and uncertainty quantification compared to prior diffusion-based methods.
By Ramiro Valdes Jara, David Chapman, Adam Meyers
arXiv:2606. 06328v1 Announce Type: new Abstract: In healthcare, multimodal time series tasks often operate on incomplete observations in practice, for example when ECG segments are lost because electrodes detach or an entire respiratory channel is unavailable during overnight monitoring.
By Ziwen Kan, Wugeng Zheng, Tianlong Chen, Song Wang
The paper introduces the Masked Diffusion Time-series Imputation Model (MDTIM), which uses a masked diffusion training paradigm to directly predict original values for time series imputation. It separates missing and observed data via a MASK token and employs Stochastic Discretization to convert continuous values into ordinal-aware tokens, preserving temporal dynamics. Experiments on multiple benchmarks show that MDTIM outperforms existing deterministic and generative baselines in robustness and scalability across various missing data scenarios.
By Dongbin Kim, Seungyun Lee, Geonwoo Shin, Jaewook Lee
arXiv:2607. 21922v1 Announce Type: new Abstract: Clinical irregular multivariate time series are shaped not only by physiological dynamics but also by the measurement process that determines when and what to observe.
By Mingyi Ma, Qingxiong Tan
The paper introduces Curriculum‑Aware Interpolate‑then‑Refine (CAIR), a two‑stage framework for imputing physiological time‑series data. CAIR first learns a coarse base curve with a bidirectional‑GRU interpolator and then refines it through three Transformer passes, trained under a random‑gap curriculum that mimics realistic missingness. Evaluations on continuous glucose monitoring and arterial pressure datasets show CAIR outperforms all baselines across MCAR, MAR, and NMAR mechanisms, especially for long gaps and value‑dependent dropout, while also preserving clinically relevant burden metrics.
By Yu-Chao Huang, Haochen Zhang, Nicholas Konz, Tianlong Chen