arXiv:2603. 03322v2 Announce Type: replace-cross Abstract: Recent advancements in Large Language Model (LLM) agents have demonstrated remarkable potential in automatic knowledge discovery.
By Chaoqun Yang, Xinyu Lin, Shulin Li, Wenjie Wang, Ruihan Guo, Fuli Feng, Tat-Seng Chua
arXiv:2607. 28229v1 Announce Type: cross Abstract: The web is increasingly accessed by AI agents rather than humans.
By Luigi Sigillo, Matteo Silvestri, Francesco Tabaro, Rajat Bhatnagar, Syed Irtaza Mubashar, Matt Jeffryes, Daljit Nijjer, Vittorio Perera, Ola Spjuth, Julio Saez-Rodriguez, Melissa Harrison, Fabio Petroni
arXiv:2607. 26070v1 Announce Type: cross Abstract: Large language model (LLM)-based agentic search systems are often evaluated as if the underlying LLM were the only component that matters, yet their measured performance also depends on the surrounding search environment: the Wikipedia snapshot, preprocessing pipeline, chunking policy, retrieval backend, tool schema, observation format, and answer submission rule.
By Guanming Xiong, Penghui Zhang
arXiv:2411. 04440v1 Announce Type: cross Abstract: Protein engineering is important for biomedical applications, but conventional approaches are often inefficient and resource-intensive.
By Yungeng Liu, Zan Chen, Yu Guang Wang, Yiqing Shen
FlyAOC is a benchmark that tests AI agents on end‑to‑end ontology curation of Drosophila scientific literature. Given a gene symbol, a brief description, a large paper corpus, and ontology resources, agents must search for evidence and produce structured annotations such as function terms, expression patterns, and historical synonyms. The benchmark contains 7,397 expert‑curated annotations across 100 genes and evaluates different agent harnesses, revealing system‑level failure modes that single‑task evaluations miss.
By Xingjian Zhang, Sophia Moylan, Ziyang Xiong, Qiaozhu Mei, Yichen Luo, Jiaqi W. Ma
arXiv:2608. 19201v1 Announce Type: cross Abstract: Bioinformatics software and databases are essential components of modern life science research, yet their mentions in the scientific literature are often inconsistent and difficult to systematically identify at scale.
By Hao Xuan, Rithvij Pasupuleti, Ben Liu, Haishuo Sun, Jun Zhang, Zijun Yao, Cuncong Zhong
arXiv:2606. 13669v1 Announce Type: new Abstract: Current LLM-based research agents have advanced through agent orchestration, yet largely overlook scientific knowledge orchestration.
By Zongsheng Cao, Bihao Zhan, Jinxin Shi, Jiong Wang, Fangchen Yu, Zhijie Zhong, Zijie Guo, Tianshuo Peng, Zhuo Liu, Yi Xie, Xiang Zhuang, Yue Fan, Runmin Ma, Shiyang Feng, Xiangchao Yan, Anran Liu, Peng Ye, Wenlong Zhang, Shufei Zhang, Chunfeng Song, Fenghua Ling, Jie Zhou, Liang He, Bo Zhang, Lei Bai
arXiv:2606. 20235v1 Announce Type: cross Abstract: Academic paper search is a core step in scientific research, and LLM-based search agents are emerging as a promising paradigm for iterative, intent-driven literature exploration.
By Tingyue Pan, Mingyue Cheng, Daoyu Wang, Yitong Zhou, Jie Ouyang, Qi Liu, Enhong Chen
arXiv:2607. 20498v1 Announce Type: new Abstract: Large language models (LLMs) augmented with tools are emerging as autonomous agents capable of using Web engine, APIs, and code to solve complex, long-horizon tasks.
By Fanjin Zhang, Zhengyang Wang, Ruixuan Huang, Kefan Zhang, Amy Xin, Yuanchun Wang, Shu Zhao, Evgeny Kharlamov, Jie Tang, Juanzi Li
arXiv:2609.05818v1 Announce Type: new
Abstract: We introduce ABLE, a benchmark for evaluating LLM agents' ability to use biological AI models (BAIMs), such as ProteinMPNN and AlphaFold3, in dual-use...
By Bryce Cai, Geetha Jeyapragasan, Samira Nedungadi, Jake Yukich, Seth Donoughe
ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.
By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
arXiv:2607. 08803v1 Announce Type: cross Abstract: The push toward large language models for biology (BioLM) has created a need for training corpora that can endow models with a genuine understanding of biology.
By Hyunjin Seo, Hyeon Hwang, Gyubok Lee, Jay Shin, Jimin Park, Taesoo Kim, Sanghoon Lee, Hongjoon Ahn, Sungjun Han, Sangwon Jung