arXiv AI

Can AI Evaluate AI Scientists? A Benchmarking Study of Autonomous Research Generation Systems Using Automated Multi-Model Review

arXiv:2607. 28631v1 Announce Type: new Abstract: AI Scientist systems capable of autonomous research have the potential to significantly accelerate scientific discovery.

arXiv AI
Jun 9

ResearchClawBench: A Benchmark for End-to-End Autonomous Scientific Research

arXiv:2606. 07591v1 Announce Type: cross Abstract: AI coding agents are increasingly used for scientific work, but their end-to-end autonomous research capability remains difficult to verify.

By Wanghan Xu, Shuo Li, Tianlin Ye, Qinglong Cao, Yixin Chen, Hengjian Gao, Yiheng Wang, Qi Li, Kun Li, Sheng Xu, Shengdu Chai, Fangchen Yu, Xiangyu Zhao, Zhangrui Zhao, Weijie Ma, Zijie Guo, Haoyu Zhou, Haoxiang Yin, Lixue Cheng, Chaofan Hu, Haoxuan Li, Lu Mi, Xuxuan Xie, Yifan Zhou, Ruizhe Chen, Zhiwang Zhou, Xingjian Guo, Yuhao Zhou, Xuming He, Shengyuan Xu, Xinyu Gu, Jiamin Wu, Mianxin Liu, Chunfeng Song, Fenghua Ling, Dongzhan Zhou, Shixiang Tang, Yuqiang Li, Mao Su, Peng Ye, Siqi Sun, Bin Wang, Xue Yang, Zhenfei Yin, Tianfan Fu, Guangtao Zhai, Wanli Ouyang, Bo Zhang, Lei Bai, Wenlong Zhang
arXiv AI
Sep 18

ScientistTwo: Pioneering the Human Knowledge Frontier with Autonomous AI

The paper introduces ScientistTwo, a fully autonomous multi‑agent framework that takes a scientific problem, establishes baselines, generates hypotheses, and coordinates specialized agents to conduct an end‑to‑end discovery cycle without human intervention. It rigorously tests and refines its methods through automated experiments, ablation studies, and a closed‑loop peer‑review engine. Benchmarking against top conferences (ICLR, ICML, NeurIPS) shows that ScientistTwo produces expert‑level, publishable papers and codebases that outperform human state‑of‑the‑art models and receive higher review ratings under automated AI review.

By Jaehyun Nam, Jinsung Yoon, Yanzhou Pan, Yubo Wang, Rui Meng, Parthasarathy Ranganathan, Tomas Pfister
arXiv AI
Jul 8

Prompt-to-Paper: Agentic AI System for Bioinformatics

arXiv:2607. 05456v1 Announce Type: new Abstract: While recent advances in large language models have enabled end-to-end automated manuscript generation, existing systems suffer from three critical deficiencies: (i) generated claims are not deterministically grounded in verifiable literature, (ii) experimental results are frequently fabricated rather than executed, and (iii) there exists no standardized, multi-dimensional framework to assess whether AI-generated manuscripts meet the quality and rigor required for real-world publication.

By Ramsha Kamran, Maheera Amjad, Zartasha Mustansar, Arsalan Shaukat, Salma Sherbaz, Muhammad U. S. Khan
arXiv AI
Jul 14

FIRE-Bench: Evaluating AI Agents on the Rediscovery of Scientific Insights

arXiv:2602. 02905v2 Announce Type: replace Abstract: Autonomous agents powered by large language models (LLMs) promise to accelerate scientific discovery end-to-end, but rigorously evaluating their capacity for verifiable discovery remains a central challenge.

By Zhen Wang, Fan Bai, Zhongyan Luo, Jinyan Su, Kaiser Sun, Xinle Yu, Jieyuan Liu, Kun Zhou, Claire Cardie, Mark Dredze, Zhiting Hu, Eric P. Xing
arXiv AI
Sep 11

OpenDiscoveryTrace: Process Traces for Evaluating AI Scientist Workflows

OpenDiscoveryTrace is a public dataset of 558 complete AI scientific agent trajectories that records the reasoning process—thoughts, tool calls, observations, errors, revision triggers, and confidence—across 124 scientific tasks in drug discovery, materials science, genomics, and literature analysis. The dataset includes seven models (three frontier models and four open‑weight models) and 60 live‑retrieval variants, providing a balanced view of performance and error patterns. Pilot analysis shows that process traces reveal behavioral differences invisible to output‑only evaluation, such as differing error rates and types among frontier models.

By Aayam Bansal, Keertan Balaji
arXiv Machine Learning
Jul 30

Can AI agents conduct open-ended AI research? Early evidence from two case studies

arXiv:2607. 27191v1 Announce Type: cross Abstract: Forecasts of explosive AI progress hinge on AI agents automating AI research.

By Peter Kirgis, Sayash Kapoor, Andrew Schwartz, Stephan Rabanser, David Africa, Konstantinos Voudouris, Viet Nguyen, Toby Pilditch, Magda Dubois, Harry Coppock, Cozmin Ududec, Nitya Nadgir, Matilda Orona, Tilman Bayer, Derrick Chan-Sew, Yue Ling, Abhishek Shetty, Helen Toner, Gillian Hadfield, Seth Lazar, Steve Newman, Shoshannah Tekofsky, Rishi Bommasani, Arvind Narayanan
arXiv AI
Aug 19

Do LLMs Know a Good Hypothesis When They See One? Logit-Based Energy Scoring Outperforms Prompted LLM-as-Judge for Scientific Hypothesis Ranking

The paper investigates whether large language models (LLMs) can reliably assess scientific hypotheses by using a logit-based energy scoring method that leverages the model’s intrinsic confidence. Across 1,323 papers in 12 disciplines, this intrinsic scoring achieved a 33.0% Hit@1 rate, outperforming a prompted listwise ranking approach that scored 16.6%. The best result, a 1‑billion‑parameter model with logit-based energy scoring, reached 53.1% Hit@1, suggesting that confidence‑based evaluation could improve trustworthy AI‑enabled scientific discovery.

By Swati Rajwal, Sanjay Das, Tirthankar Ghosal