Conditioning Protein Generation via Hopfield Pattern Multiplicity
arXiv:2603. 20115v2 Announce Type: replace Abstract: Small protein-family alignments often contain a subset of interest but not enough labeled data to train a conditional generator.
arXiv:2605. 16331v2 Announce Type: replace-cross Abstract: Protein language models are increasingly used to guide experimental and clinical decisions, yet it is often unclear whether a confident prediction reflects recognition of biological evidence or retrieval of a statistical default.
arXiv:2603. 20115v2 Announce Type: replace Abstract: Small protein-family alignments often contain a subset of interest but not enough labeled data to train a conditional generator.
arXiv:2606. 18703v1 Announce Type: new Abstract: Pretrained biological language models expose per-token probability distributions through masked-token prediction, providing the likelihood interface central to sequence design, variant scoring, and mechanistic interpretation.
arXiv:2607. 22777v1 Announce Type: cross Abstract: Protein language models learn transferable sequence representations.
Large language models (LLMs) are widely applied across chemical tasks, such as molecular property prediction, which underpins drug discovery. Molecular LLMs represent a molecule through several modalities, notably a 1D SMILES sequence or a 2D molecular graph.
arXiv:2603. 14717v2 Announce Type: replace Abstract: Generating novel protein sequences that respect a family's statistical constraints typically requires training deep generative models on thousands to millions of examples.
arXiv:2608. 10480v1 Announce Type: new Abstract: Large language models (LLMs) are widely applied across chemical tasks, such as molecular property prediction, which underpins drug discovery.
arXiv:2606. 05378v1 Announce Type: new Abstract: We test whether a single screen-and-ablate recipe -- identify attention-head circuits by task-pattern selectivity, then verify by causal ablation against a matched-random null -- produces consistent mechanistic claims across model families.
arXiv:2605. 01625v3 Announce Type: replace Abstract: Proteins are inherently multiscale physical systems whose functional properties emerge from coordinated structural organization across multiple spatial resolutions, ranging from atomic interactions to global fold topology.
arXiv:2607. 01002v1 Announce Type: cross Abstract: In long-context use, large language models frequently synthesize answers from the meaning of a relevant context span rather than literally copy-pasting them.
arXiv:2606. 16517v1 Announce Type: new Abstract: Scientific reasoning models for biology combine language models with foundation models trained on multimodal biological data, including DNA, RNA, and proteins.
arXiv:2608. 12090v1 Announce Type: new Abstract: Protein language models (PLMs) have transferred the latest advances from natural language processing to computational biology.
arXiv:2607. 20524v1 Announce Type: new Abstract: Mean cross-positional attention degradation is widely reported in transformer interpretability, yet whether it causally limits contextual retrieval remains untested.